DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and Rh5

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001285859.1	Gene:	Rh5 / 34615	FlyBaseID:	FBgn0014019	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	170/365 - (46%)
Similarity:	237/365 - (64%)	Gaps:	6/365 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PLRPEA---RSSGNGDLQFLGWNVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGN 72
            |..|:|   .|.|:|.:..:|...|.:....:..||....|.|...|....:.:|.|..:|..||
  Fly     6 PSGPQAYVNDSLGDGSVFPMGHGYPAEYQHMVHAHWRGFREAPIYYHAGFYIAFIVLMLSSIFGN 70

  Fly    73 GMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSG 137
            |:||||||||||||||||:.:||||:|||.||...|.::.|:.......|:..|.|:|..|..||
  Fly    71 GLVIWIFSTSKSLRTPSNLLILNLAIFDLFMCTNMPHYLINATVGYIVGGDLGCDIYALNGGISG 135

  Fly   138 IGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTS 202
            :||.:|||.|.:|||..|:.|::..:::.:.|::.:..||:.||:.||||.|.|.|:.|||:||:
  Fly   136 MGASITNAFIAFDRYKTISNPIDGRLSYGQIVLLILFTWLWATPFSVLPLFQIWGRYQPEGFLTT 200

  Fly   203 CSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNV 267
            ||||||::..:.||||.|||.:|:|.|..|||..|.::..||..|||.|.||||||||:||.:|.
  Fly   201 CSFDYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYKLFTHVRVHEKMLAEQAKKMNVKSLSANA 265

  Fly   268 DKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPF 332
            :....:.|:||||||:.|..||.::||||.|::|||.||::.|:||..:|:|...||.|:|:||:
  Fly   266 NADNMSVELRIAKAALIIYMLFILAWTPYSVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPW 330

  Fly   333 VYAISHPRYRLELQKRCPWLGVNEK---SGEISSAQSTTT 369
            |||.|||:|||||::|.||||:.||   ||.....:|..:
  Fly   331 VYATSHPKYRLELERRLPWLGIREKHATSGTSGGQESVAS 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	145/289 (50%)
		TM helix 1	57..81	CDD:320207	11/23 (48%)
		TM helix 2	90..111	CDD:320207	11/20 (55%)
		TM helix 3	127..149	CDD:320207	11/21 (52%)
		TM helix 4	170..186	CDD:320207	5/15 (33%)
		TM helix 5	215..238	CDD:320207	13/22 (59%)
		TM helix 6	279..301	CDD:320207	12/21 (57%)
		TM helix 7	313..338	CDD:320207	12/24 (50%)
Rh5	NP_001285859.1	7tm_4	60..>236	CDD:304433	87/175 (50%)
Rh5	NP_001285859.1	7tm_1	69..332	CDD:278431	133/262 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D32029at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42416
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24240
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950