DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rh4 and Opn5

DIOPT Version :9

Sequence 1:NP_476701.1 Gene:Rh4 / 39887 FlyBaseID:FBgn0003250 Length:378 Species:Drosophila melanogaster
Sequence 2:XP_038939470.1 Gene:Opn5 / 316259 RGDID:727869 Length:533 Species:Rattus norvegicus


Alignment Length:404 Identity:99/404 - (24%)
Similarity:175/404 - (43%) Gaps:69/404 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 VPPDQIQYIPEHWLTQLEPPAS-----MHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSN 90
            :|.|  :.:| |:|...:|.||     ...:.|.:...:...||.|||.|:::.|..|....|:.
  Rat     8 LPQD--ERLP-HYLRDEDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAE 69

  Fly    91 MFVLNLAVFDL-IMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNV 154
            :..:||||.|| |..:..|..|.:.|...:..|...|:.:...|.:.|.|:.:|..|:..|||..
  Rat    70 IMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWFGCRWYGWAGFFFGCGSLITMTAVSLDRYLK 134

  Fly   155 ITKPMNRNMTFTK--AVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDY--LSDNFDTR 215
            |.. ::..:...:  |.|...:||.|.:.|..:||....| :.||.:.|||:.|:  ...:...:
  Rat   135 ICY-LSYGVWLKRKHAYICLAVIWAYASFWTTMPLVGLGD-YAPEPFGTSCTLDWWLAQASGGGQ 197

  Fly   216 LFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKM-------------------NVE 261
            :|:.:|.||..:.||.:|::.|::|:..|.|..|.:.....::                   :.|
  Rat   198 VFILSILFFCLLLPTAVIVFSYAKIIAKVKSSSKEVAHFDSRIHSSHVLEVKLTKGLVRADSSPE 262

  Fly   262 SLRSNVDKSKE--------TAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMI 318
            ||..:|..:.|        .:..|::..|:.||..|.::|.||.|:|:..|||..:.:....:::
  Rat   263 SLPRSVFSTAEPINCHVLSISHSRVSTVAMLICAGFLIAWIPYAVVSVWSAFGRPNSIPIQLSVV 327

  Fly   319 PACTCKLVACIDPFVYAISHPRYRL---------------------ELQKRCPWLGVNEKSGEIS 362
            |....|..|..:|.:|.:...|:..                     ::.||    ..:.|||:|.
  Rat   328 PTLLAKSAAMYNPIIYQVIDYRFACCQTGGLRATKKKSLEDFSDLNQILKR----NSSTKSGQIG 388

  Fly   363 SAQSTTTQEQQQTT 376
            :  ..|.:|..:.|
  Rat   389 N--KDTAEEHDRGT 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rh4NP_476701.1 7tmA_photoreceptors_insect 55..345 CDD:320207 82/342 (24%)
TM helix 1 57..81 CDD:320207 7/23 (30%)
TM helix 2 90..111 CDD:320207 8/21 (38%)
TM helix 3 127..149 CDD:320207 5/21 (24%)
TM helix 4 170..186 CDD:320207 5/15 (33%)
TM helix 5 215..238 CDD:320207 7/22 (32%)
TM helix 6 279..301 CDD:320207 8/21 (38%)
TM helix 7 313..338 CDD:320207 5/24 (21%)
Opn5XP_038939470.1 7tmA_Opsin5_neuropsin 34..353 CDD:320202 82/320 (26%)
TM helix 1 36..60 CDD:320202 7/23 (30%)
TM helix 2 69..91 CDD:320202 8/21 (38%)
TM helix 3 107..129 CDD:320202 5/21 (24%)
TM helix 4 151..167 CDD:320202 5/15 (33%)
TM helix 5 197..220 CDD:320202 7/22 (32%)
TM helix 6 251..310 CDD:320202 14/58 (24%)
TM helix 7 322..347 CDD:320202 5/24 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D704940at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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