Protein Alignment Rh4 and OPN3

DIOPT Version :10

• Sequence 1: NP_476701.1
• Gene: Rh4 / 39887
• FlyBaseID: FBgn0003250
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_055137.2
• Gene: OPN3 / 23596
• HGNCID: 14007
• Length: 402
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 87/356 - (24%)
• Similarity: 149/356 - (41%)
• Gaps: 66/356 - (18%)

  Fly    70 VGNG-MVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKAPIFIYNSFHRGFALGNTW------CQ 127
            |||. :|:.::...:.||||:::.::|:::.||::.|....|.:.|     .|.|.|      |.
Human    56 VGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVS-----CLRNGWVWDTVGCV 115

  Fly   128 IFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWD 192
            .....||..||.:..|...:.|:||  |.....|.:.|:.|......||||...|...||.. |:
Human   116 WDGFSGSLFGIVSIATLTVLAYERY--IRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLG-WN 177

  Fly   193 RFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK 257
            |::.:.:...|:.|:.|.:.:...||..:|....|.|..:|.:.|    ||:....:.||
Human   178 RYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCY----GHILYSIRMLR----- 233

  Fly   258 MNVESLRS-NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPAC 321
             .||.|:: .|.|..: .|.::||....:.|.|.|.|.||.|:..:...|...|:||..:::...
Human   234 -CVEDLQTIQVIKILK-YEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYL 296

  Fly   322 TCKLVACIDPFVYAISHPRYRLELQK-------RC-------PWLG---------VNEKSGE--- 360
            ..|.....:|.:|.....::|..|.:       ||       |..|         :::|.|:
Human   297 FAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRPK 361

  Fly   361 -------------ISSAQSTTTQEQQQTTAA 378
                         |:|.:|.:..:..:|..:
Human   362 KKVTFNSSSIIFIITSDESLSVDDSDKTNGS 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	76/282 (27%)
		TM helix 1	56..82	CDD:320207	4/12 (33%)
		TM helix 2	89..114	CDD:320207	5/24 (21%)
		TM helix 3	126..156	CDD:320207	9/29 (31%)
		TM helix 4	166..186	CDD:320207	6/19 (32%)
		TM helix 5	214..243	CDD:320207	7/28 (25%)
		TM helix 6	273..303	CDD:320207	10/29 (34%)
		TM helix 7	313..338	CDD:320207	4/24 (17%)
OPN3	NP_055137.2	7tmA_Encephalopsin	58..316	CDD:320206	73/276 (26%)
		TM helix 2	76..103	CDD:320206	6/31 (19%)
		TM helix 3	114..144	CDD:320206	10/31 (32%)
		TM helix 4	152..174	CDD:320206	7/21 (33%)
		TM helix 5	199..229	CDD:320206	9/33 (27%)
		TM helix 6	248..278	CDD:320206	10/30 (33%)
		TM helix 7	288..313	CDD:320206	4/24 (17%)