Protein Alignment Rh4 and Opn1mw

DIOPT Version :10

• Sequence 1: NP_476701.1
• Gene: Rh4 / 39887
• FlyBaseID: FBgn0003250
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_032132.1
• Gene: Opn1mw / 14539
• MGIID: 1097692
• Length: 359
• Species: Mus musculus
• Alignment Length: 370
• Identity: 86/370 - (23%)
• Similarity: 147/370 - (39%)
• Gaps: 48/370 - (12%)

  Fly    18 SSGNGDLQFLGWNVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTS 82
            :|..|..:...:::.|..:.::...|:                 |.:..||...||:|:......
Mouse    29 NSTKGPFEGPNYHIAPRWVYHLTSTWM-----------------ILVVVASVFTNGLVLAATMRF 76

  Fly    83 KSLRTPSNMFVLNLAVFDLI-MCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAA 146
            |.||.|.|..::||||.||. ..:.:.|.:.|..:..|.||:..|.|...|.|..||....:.|.
Mouse    77 KKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAI 141

  Fly   147 IGYDRYNVITKPMNRNMTF-TKAVIMNIII-WLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLS 209
            |.::|:.|:.||.. |:.| .|...:.|:. |::...|...|:.. |.|:.|.|..|||..|..|
Mouse   142 ISWERWLVVCKPFG-NVRFDAKLATVGIVFSWVWAAIWTAPPIFG-WSRYWPYGLKTSCGPDVFS 204

  Fly   210 DNF--DTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKE 272
            ...  ..:.::..:.....:.|..:|:..|.|:       ..|:|..||:.. ||      :|.:
Mouse   205 GTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQV-------WLAIRAVAKQQK-ES------ESTQ 255

  Fly   273 TAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAIS 337
            .||..:.:..:.:.|.:.:.|.||...:............|....:|:...|.....:|.:|...
Mouse   256 KAEKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFM 320

  Fly   338 HPRYR---LEL-QKRCPWLGVNEKSGEISSAQSTTTQEQQQTTAA 378
            :.::|   |.| .|:.      :.|.|:||...|........:.|
Mouse   321 NRQFRNCILHLFGKKV------DDSSELSSTSKTEVSSVSSVSPA 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	74/297 (25%)
		TM helix 1	56..82	CDD:320207	6/25 (24%)
		TM helix 2	89..114	CDD:320207	8/25 (32%)
		TM helix 3	126..156	CDD:320207	10/29 (34%)
		TM helix 4	166..186	CDD:320207	4/20 (20%)
		TM helix 5	214..243	CDD:320207	4/28 (14%)
		TM helix 6	273..303	CDD:320207	6/29 (21%)
		TM helix 7	313..338	CDD:320207	5/24 (21%)
Opn1mw	NP_032132.1	Required for 11-cis-retinal regeneration. /evidence=ECO:0000250|UniProtKB:P04001	12..38		2/8 (25%)
		7tm_GPCRs	37..328	CDD:475119	75/323 (23%)
		TM helix 1	51..75	CDD:320209	7/40 (18%)
		TM helix 2	84..106	CDD:320209	8/21 (38%)
		TM helix 3	122..144	CDD:320209	7/21 (33%)
		TM helix 4	166..182	CDD:320209	3/15 (20%)
		TM helix 5	212..235	CDD:320209	2/22 (9%)
		TM helix 6	262..284	CDD:320209	4/21 (19%)
		TM helix 7	296..321	CDD:320209	5/24 (21%)