Protein Alignment Rh4 and RRH

DIOPT Version :10

• Sequence 1: NP_476701.1
• Gene: Rh4 / 39887
• FlyBaseID: FBgn0003250
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_006574.1
• Gene: RRH / 10692
• HGNCID: 10450
• Length: 337
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 73/295 - (24%)
• Similarity: 139/295 - (47%)
• Gaps: 23/295 - (7%)

  Fly    54 HYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDL-IMCLKAPIFIYNSFHR 117
            |.::..:.|.....|.:.|.:|:.||...|.||||:|..::||||.|: :..:..|:...:..:.
Human    25 HNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIGYPMSAASDLYG 89

  Fly   118 GFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKP-MNRNMTFTKAVIMNIIIWLYCTP 181
            .:..|...||::|.:..:.|:.:......:..|||..|..| :.|.||....:.:.:..|:....
Human    90 SWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTTNTYIGLILGAWINGLF 154

  Fly   182 WVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVG---TIFFFSFVCP-TLMILYYYSQIVG 242
            |.::|:.. |..:.|:....:|:.::..::   |.||.   |:...:|:.| |:|...||
Human   155 WALMPIIG-WASYAPDPTGATCTINWRKND---RSFVSYTMTVIAINFIVPLTVMFYCYY----- 210

  Fly   243 HVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGD 307
            ||   ..:::........|||  |.|.|.   :|.:.|.::.:..:|.|:|:||.::.|..:|||
Human   211 HV---TLSIKHHTTSDCTESL--NRDWSD---QIDVTKMSVIMICMFLVAWSPYSIVCLWASFGD 267

  Fly   308 KSLLTPGATMIPACTCKLVACIDPFVYAISHPRYR 342
            ...:.|...:|.....|.....:|.:|.:::.::|
Human   268 PKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFR 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	72/294 (24%)
		TM helix 1	56..82	CDD:320207	6/25 (24%)
		TM helix 2	89..114	CDD:320207	7/25 (28%)
		TM helix 3	126..156	CDD:320207	7/29 (24%)
		TM helix 4	166..186	CDD:320207	2/19 (11%)
		TM helix 5	214..243	CDD:320207	10/32 (31%)
		TM helix 6	273..303	CDD:320207	8/29 (28%)
		TM helix 7	313..338	CDD:320207	5/24 (21%)
RRH	NP_006574.1	7tmA_Peropsin	26..305	CDD:320201	72/294 (24%)
		TM helix 1	27..53	CDD:320201	6/25 (24%)
		TM helix 2	60..87	CDD:320201	7/26 (27%)
		TM helix 3	98..128	CDD:320201	7/29 (24%)
		TM helix 4	141..159	CDD:320201	2/17 (12%)
		TM helix 5	186..216	CDD:320201	11/37 (30%)
		TM helix 6	233..263	CDD:320201	9/32 (28%)
		TM helix 7	273..298	CDD:320201	5/24 (21%)