Protein Alignment Rh4 and tmtopn

DIOPT Version :10

• Sequence 1: NP_476701.1
• Gene: Rh4 / 39887
• FlyBaseID: FBgn0003250
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001304832.1
• Gene: tmtopn / 100488877
• XenbaseID: XB-GENE-1018915
• Length: 382
• Species: Xenopus tropicalis
• Alignment Length: 333
• Identity: 82/333 - (24%)
• Similarity: 161/333 - (48%)
• Gaps: 28/333 - (8%)

  Fly    49 PPA-----SMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCL-KA 107
            |||     :.|.::.|....:....::.|..|:.||....::|||.||.:||::|.||::|: ..
 Frog    26 PPATGLSRTAHSVVAVCLGCILVLGSLYNSFVLLIFVKFTAIRTPINMILLNISVSDLLVCIFGT 90

  Fly   108 PIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMT-FTKAVIM 171
            |....:|...|:.||...|:.:....|..|:.:.::.:.:.|:||..:.|....:|| :.|:.:.
 Frog    91 PFSFVSSVSGGWLLGQQGCKWYGFCNSLFGLVSMISLSMLSYERYLTVLKCTKADMTDYKKSWLC 155

  Fly   172 NIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYY 236
            .|:.|||...|.:.||.. |..:..|...|:||..:.|.:.:...::..:|.|..|.|..::::.
 Frog   156 IIVSWLYSLCWTLPPLIG-WSSYGLESSGTTCSVVWHSKSSNNISYIVCLFLFCLVLPLFIMIFC 219

  Fly   237 YSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSL 301
            |..||       :.:|.|..::|:.:.:..        |.|:....:.:...:.:.|.|||::||
 Frog   220 YGHIV-------RVIRGQVCRINMTTAQKR--------EHRLLFMVVCMVTCYLLCWMPYGLVSL 269

  Fly   302 IGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVNEKSGEISSAQS 366
            :.|||...::||..::||:...|....|:|.:|...:.::     .||....:..:||...:...
 Frog   270 MTAFGKPGMITPTVSIIPSILAKSSTFINPLIYIFMNKQF-----YRCFIALIKCESGPHHNENI 329

  Fly   367 TTTQEQQQ 374
            :|:::.::
 Frog   330 STSRQSRE 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	73/291 (25%)
		TM helix 1	56..82	CDD:320207	5/25 (20%)
		TM helix 2	89..114	CDD:320207	9/25 (36%)
		TM helix 3	126..156	CDD:320207	6/29 (21%)
		TM helix 4	166..186	CDD:320207	6/19 (32%)
		TM helix 5	214..243	CDD:320207	7/28 (25%)
		TM helix 6	273..303	CDD:320207	8/29 (28%)
		TM helix 7	313..338	CDD:320207	7/24 (29%)
tmtopn	NP_001304832.1	7tm_GPCRs	38..313	CDD:475119	74/295 (25%)
		TM helix 1	39..63	CDD:410628	5/23 (22%)
		TM helix 2	72..94	CDD:410628	9/21 (43%)
		TM helix 3	110..132	CDD:410628	2/21 (10%)
		TM helix 4	154..170	CDD:410628	5/15 (33%)
		TM helix 5	198..221	CDD:410628	4/22 (18%)
		TM helix 6	247..269	CDD:410628	4/21 (19%)
		TM helix 7	281..306	CDD:410628	7/24 (29%)