DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rh4 and XB5957215

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	XP_031759018.1	Gene:	XB5957215 / 100485437	XenbaseID:	XB-GENE-5957216	Length:	582	Species:	Xenopus tropicalis

Alignment Length:	347	Identity:	110/347 - (31%)
Similarity:	173/347 - (49%)	Gaps:	32/347 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 QLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIM-CLKAPI 109
            ||:.||.:.|.:|.|.:.:.....:||.:|::.|.::|.|||..|.|::|||:.|.:| ..:||:
Frog    19 QLDAPAQVLYTIGSFILIIGFVGIIGNLLVLYAFYSNKKLRTAPNYFIMNLAISDFLMSATQAPV 83

  Fly   110 FIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMN----RNMTFTKAVI 170
            ...:|.||.:.||...|.::|..|:..||.:.||..||..:||.|||||:.    .:...|..||
Frog    84 CFLSSLHREWILGEIGCNVYAFCGALFGITSMMTLLAISVNRYIVITKPLQSIQWSSKKRTSQVI 148

  Fly   171 MNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILY 235
              :::|:|...|.:.||.. |..:||||...||::||::.....:.:...:....|..|.::|.:
Frog   149 --VLVWMYSFMWSLAPLLG-WSSYVPEGLRISCTWDYVTSTTSNKSYTMMLCCCVFFIPLIIISH 210

  Fly   236 YYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETA----EIRIAKAAITICFLFFVSWTPY 296
            .|       |....|:|...:  ||:.|.|...:|..|.    |.::||.|..|..::.:||:||
Frog   211 CY-------FFMFLAIRSTGR--NVQKLGSYGRQSFLTPTMKNEWKMAKIAFVIIIVYVLSWSPY 266

  Fly   297 GVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVNEKS--- 358
            ..::||...|....|||.:..:||...|..|..:|.:|.|.||:||..:.|..|.|....|.
Frog   267 ACVTLIAWAGHGKSLTPYSKTVPAVIAKASAIYNPIIYGIIHPKYRETIHKTVPCLRFLIKEPKK 331

  Fly   359 --------GEISSAQSTTTQEQ 372
                    |.|.|.||...:::
Frog   332 DCFESSVRGSIYSRQSLVARKK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	97/298 (33%)
		TM helix 1	57..81	CDD:320207	6/23 (26%)
		TM helix 2	90..111	CDD:320207	9/21 (43%)
		TM helix 3	127..149	CDD:320207	8/21 (38%)
		TM helix 4	170..186	CDD:320207	4/15 (27%)
		TM helix 5	215..238	CDD:320207	3/22 (14%)
		TM helix 6	279..301	CDD:320207	8/21 (38%)
		TM helix 7	313..338	CDD:320207	8/24 (33%)
XB5957215	XP_031759018.1	7tmA_Melanopsin	28..315	CDD:320458	97/298 (33%)
		TM helix 1	30..54	CDD:320458	6/23 (26%)
		TM helix 2	63..85	CDD:320458	9/21 (43%)
		TM helix 3	101..123	CDD:320458	8/21 (38%)
		TM helix 4	146..162	CDD:320458	5/17 (29%)
		TM helix 5	190..213	CDD:320458	4/29 (14%)
		TM helix 6	249..271	CDD:320458	8/21 (38%)
		TM helix 7	283..308	CDD:320458	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9343
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050