DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rh4 and opn6a

DIOPT Version :9

Sequence 1:	NP_476701.1	Gene:	Rh4 / 39887	FlyBaseID:	FBgn0003250	Length:	378	Species:	Drosophila melanogaster
Sequence 2:	NP_001096345.1	Gene:	opn6a / 100124934	XenbaseID:	XB-GENE-5872637	Length:	400	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	87/367 - (23%)
Similarity:	151/367 - (41%)	Gaps:	55/367 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PEHW------LTQLEPPASM--HYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNL 96
            |..|      |.|.|.|.:.  ..::|::.:.|...|..||.:||::....::...|::....||
Frog     8 PAPWRNNNLTLLQKENPLTEQGETIIGIYLLALGWLSWFGNSIVIFVLYKQRANLLPTDYLTFNL 72

  Fly    97 AVFDLIMCL----KAPIFIYNSFH-RGFALGNTW-CQIFASIGSYSGIGAGMTNAAIGYDRYNVI 155
            ||.|....:    :..|.|:|.|. .||.:.:.| ||:...:....|:.:..|...|...||...
Frog    73 AVSDASTSVFGYSRGIIEIFNVFRDDGFLITSIWTCQVDGFLTLLFGLASINTLTLISVTRYIKG 137

  Fly   156 TKPMNRNMTFTKAVIMNI-IIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDT--RLF 217
            ..|...|.....::.::: :||:....|.|.||.. |..:....|.| |..|:...:|.|  :.:
Frog   138 CHPQRANCISNGSITISLALIWIAALFWSVAPLLG-WGSYRDRMYGT-CEIDWTKASFSTIYKSY 200

  Fly   218 VGTIFFFSFVCPTLMILYYYSQIVGHV-----FSHEKALREQAKKMNVESLRSNVDKSKETAEIR 277
            :.:||...|..|.:::::.|..|:..|     .:.|..|.|:.:||                |..
Frog   201 IISIFICCFFLPVMVMVFCYVSIINTVKSSRALTSEGDLSERQRKM----------------ERD 249

  Fly   278 IAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGAT-MIPACTCKLVACIDPFVYAISHPRY 341
            :.:.::.||..|.|:|:||.|:|:..|.|   ...|..| ::.|...|..:..:|.:|.....::
Frog   250 VTRVSVVICTAFIVAWSPYAVISMWSACG---YYVPSLTSILAALFAKSASFYNPLIYFGMSSKF 311

  Fly   342 RLELQKRCPWLGV-----------NEKSGEISSAQSTTTQEQ 372
            |.:|....|....           ::|.|....|:..|..||
Frog   312 RKDLCVVLPCAKAQKDPVKLKRYKDKKQGSAPRAREQTEIEQ 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rh4	NP_476701.1	7tmA_photoreceptors_insect	55..345	CDD:320207	73/304 (24%)
		TM helix 1	57..81	CDD:320207	7/23 (30%)
		TM helix 2	90..111	CDD:320207	6/24 (25%)
		TM helix 3	127..149	CDD:320207	4/21 (19%)
		TM helix 4	170..186	CDD:320207	4/16 (25%)
		TM helix 5	215..238	CDD:320207	4/22 (18%)
		TM helix 6	279..301	CDD:320207	8/21 (38%)
		TM helix 7	313..338	CDD:320207	6/25 (24%)
opn6a	NP_001096345.1	7tmA_Opsin5_neuropsin	31..315	CDD:320202	73/304 (24%)
		TM helix 1	32..58	CDD:320202	7/25 (28%)
		TM helix 2	65..92	CDD:320202	6/26 (23%)
		TM helix 3	108..138	CDD:320202	7/29 (24%)
		TM helix 4	151..169	CDD:320202	4/17 (24%)
		TM helix 5	197..227	CDD:320202	6/29 (21%)
		TM helix 6	245..275	CDD:320202	12/45 (27%)
		TM helix 7	283..308	CDD:320202	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D310934at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010