DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and AKR1

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_010550.1	Gene:	AKR1 / 851857	SGDID:	S000002672	Length:	764	Species:	Saccharomyces cerevisiae

Alignment Length:	266	Identity:	63/266 - (23%)
Similarity:	104/266 - (39%)	Gaps:	40/266 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FMMIGCKYIANANPKRFAKIVHPS---------------AVGFVLVGTVLFFSVEMFY-MLPRIY 51
            |::|....:|.|..|...|.|.||               .:..|..||:|:.::..|: ::||.:
Yeast   348 FVIIVLFLLAIATNKGLNKFVLPSYGRMGVHNVTLLRSPLLSGVFFGTLLWVTIVWFFKVMPRTF 412

  Fly    52 DTDGLFFKIAWLMALFIVYNLLGNML----AC------HRN-SSAVTSLPKDRQIPCPEEKHLWH 105
             :|..:..|..|:.|..|:.|.|.::    .|      |.| ...:::|   .:|...:.|   :
Yeast   413 -SDEQYTNILMLVILVSVFYLFGQLVIMDPGCLPEETDHENVRQTISNL---LEIGKFDTK---N 470

  Fly   106 FCDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLATHVN 170
            ||....:..|.||....:....:.|.||:|.:....||..|::.|.:|...|..|....||..:.
Yeast   471 FCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDVGLKNHKAFIFFITLMESGIFTFLALCLE 535

  Fly   171 LLIIDEQIRRQYVVLHFSRFFLFLKPMSCELIALNISFIINIYAC-----ILSLIML-GYQIPAL 229
            .....|.........:...|.|....:...||.....|:|.::|.     :.|||.: .:||...
Yeast   536 YFDELEDAHEDTSQKNGKCFILGASDLCSGLIYDRFVFLILLWALLQSIWVASLIFVQAFQICKG 600

  Fly   230 YLNTTF 235
            ..||.|
Yeast   601 MTNTEF 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	35/142 (25%)
AKR1	NP_010550.1	ANK repeat	75..101	CDD:293786
		ANKYR	78..270	CDD:223738
		ANK repeat	103..140	CDD:293786
		ANK repeat	142..173	CDD:293786
		ANK repeat	213..244	CDD:293786
		ANK repeat	246..271	CDD:293786
		COG5273	363..725	CDD:227598	58/251 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900