DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_082655.1	Gene:	Zdhhc4 / 72881	MGIID:	1920131	Length:	343	Species:	Mus musculus

Alignment Length:	254	Identity:	62/254 - (24%)
Similarity:	103/254 - (40%)	Gaps:	59/254 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LFFKIAWLMALFIV--YNLLGNMLACHRNSSAVT--------SLPKDRQIPCPEEKHLWHFCDHC 110
            |.|.:.:|:..:::  .||:...|.|..|...:|        .:.|...:..|:...    |..|
Mouse    94 LEFSLPYLLLPYVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSR----CPTC 154

  Fly   111 QMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLAT-----HVN 170
            .:..|.||.||::|:.|:.|.||||::...|:|..|.|||..:.:.: ..|..::||     .:.
Mouse   155 DLRKPARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTL-TASAATIATVTAAFLLR 218

  Fly   171 LLIIDEQIRRQYV--VLHFSRF-------FLFLKPMSCELIALNISFIINIYACILSLIMLGYQI 226
            |:.:.:..:..|:  |.||...       .|||   :...|...:.|:|     :||:::.||..
Mouse   219 LVTVSDLYQETYLDDVGHFQAVDTVFLIQHLFL---AFPRIVFLLGFVI-----VLSMLLAGYLC 275

  Fly   227 PALYLNTTFYTPKDYRYNQGLLGNFMAFMGKRGLWTFISPSIRSPLPHDGTKWQTKQAP 285
            .||||..|..|..::               .:|.|.:..   |.||    ..|.....|
Mouse   276 FALYLAATNQTTNEW---------------YKGDWAWCQ---RWPL----VAWSPSAEP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	43/149 (29%)
Zdhhc4	NP_082655.1	DHHC	151..292	CDD:396215	44/164 (27%)
Zdhhc4	NP_082655.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3877
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760