DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and Zdhhc17

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_766142.2	Gene:	Zdhhc17 / 320150	MGIID:	2445110	Length:	632	Species:	Mus musculus

Alignment Length:	251	Identity:	64/251 - (25%)
Similarity:	78/251 - (31%)	Gaps:	100/251 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 FFSVEMFYMLP-RIYDTDGLFFKIAW-------LMALFIVYNLLGNMLACHRNSSAVTSLPKDRQ 94
            ||...|...|| .||.....:..:.|       |..|||....|.|.:|...|..  .|...|..
Mouse   349 FFDHSMHSALPLGIYLATKFWMYVTWFFWFWNDLNFLFIHLPFLANSVALFYNFG--KSWKSDPG 411

  Fly    95 I--PCPEEK-------------HLWHFCDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGH 144
            |  ...|:|             .|..||..|.:..|.||.||.||..||.:.||||.:...|||.
Mouse   412 IIKATEEQKKKTIVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGA 476

  Fly   145 TNYRYFFWFTVYMHIGSLLSLATHVNLLIIDEQIRRQYVVLHFSRFFLFLKPMSCELIALNISFI 209
            .|:|||..:.                                   |||..  |.|.:
Mouse   477 GNHRYFMGYL-----------------------------------FFLLF--MICWM-------- 496

  Fly   210 INIYACILSLIMLGYQIPALYLNTTFYTPKDYRYNQGLLGNFMAFMGKRGLWTFIS 265
              ||.|:      .|.  .|:..|| ||                   |.|.||:|:
Mouse   497 --IYGCV------SYW--GLHCETT-YT-------------------KDGFWTYIT 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	37/148 (25%)
Zdhhc17	NP_766142.2	Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000269\|PubMed:25253725	11..305
		ANK repeat	89..120	CDD:293786
		PHA03095	100..>352	CDD:222980	2/2 (100%)
		ANK repeat	122..154	CDD:293786
		ANK repeat	156..187	CDD:293786
		Ank_2	161..255	CDD:372319
		ANK repeat	189..221	CDD:293786
		ANK repeat	224..255	CDD:293786
		DHHC	438..568	CDD:366691	42/160 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810