DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and ZDHHC23

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001307395.1	Gene:	ZDHHC23 / 254887	HGNCID:	28654	Length:	435	Species:	Homo sapiens

Alignment Length:	194	Identity:	49/194 - (25%)
Similarity:	79/194 - (40%)	Gaps:	61/194 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 KHLWHFCDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSL 165
            |..|  |..||::.|.|:|||::|..|:.|.||||::..:|||.:|::.|.       :..|:.|
Human   257 KEDW--CAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFI-------LALLIFL 312

  Fly   166 ATHVN--LLIIDEQIRRQYVVLHFSRFFLFLKPMSCELIALNISFIINI--------------YA 214
            .|.|.  .|.:|...|.:.|   |:..|.      |..:..|.|..::.              |.
Human   313 LTSVYGITLTLDTICRDRSV---FTALFY------CPGVYANYSSALSFTCVWYSVIITAGMAYI 368

  Fly   215 CILSLIMLGYQIP------------------ALYLNTTFYTPKDYRYNQGLLGNFMAF--MGKR 258
            .::.||.:.|.:.                  .|.::|.       :||:|.|.|:..|  :|.|
Human   369 FLIQLINISYNVTEREVQQALRQKTGRRLLCGLIVDTG-------QYNRGFLRNWHQFSTLGTR 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	41/168 (24%)
ZDHHC23	NP_001307395.1	MerC	96..>151	CDD:281231
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	215..255
		zf-DHHC	258..384	CDD:279823	38/143 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810