DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and Zdhhc2

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_659564.3	Gene:	Zdhhc2 / 246326	RGDID:	628681	Length:	366	Species:	Rattus norvegicus

Alignment Length:	120	Identity:	36/120 - (30%)
Similarity:	59/120 - (49%)	Gaps:	17/120 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 FCDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLATHVN 170
            :||.|:::.|.|..||.||:.|||:.||||.:...|||.:||::|..|..|..:..|...||.:.
  Rat   127 YCDRCRLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQ 191

  Fly   171 LLI-------IDEQIRRQYVVLHFSRFFLFLKPMSCELIALNISFIINIYACILS 218
            ..|       .|.|.:       |...|||   .:..:.::::|.:...:..::|
  Rat   192 YFIRFWTNGLPDTQAK-------FHIMFLF---FAAAMFSVSLSSLFGYHCWLVS 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	36/120 (30%)
Zdhhc2	NP_659564.3	DHHC	19..301	CDD:418707	36/120 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..366
		Mediates localization to plasma membrane and recycling endosomes. /evidence=ECO:0000250\|UniProtKB:P59267	298..366
		Non-canonical dileucine endocytic signal. /evidence=ECO:0000250\|UniProtKB:P59267	334..335
		NPxY-like endocytic signal. /evidence=ECO:0000250\|UniProtKB:P59267	357..360
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810