DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13029 and ZDHHC15

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens

Alignment Length:	191	Identity:	54/191 - (28%)
Similarity:	80/191 - (41%)	Gaps:	48/191 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 FCDHCQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLATHVN 170
            |||.|.::.|.|..||.||..|:|:.||||.:...|:|.:||::|..|..| .:...|.:||.|.
Human   130 FCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAY-SVLYCLYIATTVF 193

  Fly   171 LLIID------EQIRRQYVVLHFSRFFLFLKPMSCELIALNISFIINIYACILSLIMLGYQIPAL 229
            ...|.      ..:|.::.||    |.||:..|          |.:::      :|:.||....:
Human   194 SYFIKYWRGELPSVRSKFHVL----FLLFVACM----------FFVSL------VILFGYHCWLV 238

  Fly   230 YLNTT----FYT------PKDYRYNQGLLGNFMAFMG-KRGLWTFISPSIRSPL---PHDG 276
            ..|.|    |.|      |:...:|.|.:.|.....| |:..|..       |:   |.||
Human   239 SRNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDKKKFWLI-------PIGSSPGDG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	41/139 (29%)
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	54/191 (28%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810