DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13029 and si:ch211-223a10.1

DIOPT Version :9

Sequence 1:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	XP_009305694.1	Gene:	si:ch211-223a10.1 / 101884554	ZFINID:	ZDB-GENE-090313-86	Length:	544	Species:	Danio rerio

Alignment Length:	279	Identity:	65/279 - (23%)
Similarity:	116/279 - (41%)	Gaps:	82/279 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FAKIVHPSAVGFVLVG----TVLFFSVEMFYMLPRIYDTD--------------GLFFKIAWLMA 65
            |.::.:|..:|.:..|    ||.|    ::.::|..:...              |||:|
Zfish   299 FQRLPNPVYLGTLTAGLIHSTVCF----LYKIIPSFWPAHTLLHLSLVHFCVLAGLFWK------ 353

  Fly    66 LFIVYNLLGNMLACHRNS--SAVTSLPKDRQIPCPEEKHLWHFCDHCQMLVPPRSWHCKVCECCI 128
              ::....|.:.....:|  |::..|.:..|.|.       .||.:|:::......||::|:.||
Zfish   354 --VLKQSPGQLKDADTDSRFSSIGDLMEAGQSPD-------RFCIYCELIQVENCKHCRLCDMCI 409

  Fly   129 LRRDHHCIFTATCVGHTNYRYFFWFTVYMHIGSLLSLATHVNLLIIDEQIRRQYVVLHFSRFFLF 193
            ...||||:|...|||..|:|.|..|.:.|.:..|:.:.:.:                    |:|:
Zfish   410 KDYDHHCLFINQCVGRENHRTFILFLMSMVMAHLIFILSAI--------------------FYLY 454

  Fly   194 LKPMSCEL-----IALNISFIINIYAC-ILSLI----MLGYQIPALYLNTTFYTPKDY-RYN--- 244
            ||....:|     :|...::::.:... :|||.    :||.|:.|:...||.|    | ||:
Zfish   455 LKVSGLQLSDWGSVAGREAWVLLLTLLNLLSLFWVGWLLGEQLDAISRGTTTY----YRRYDLKG 515

  Fly   245 ---QGLLGNFMAFM--GKR 258
               :..||..::|:  |||
Zfish   516 PSKRQRLGTVVSFLLEGKR 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	37/145 (26%)
si:ch211-223a10.1	XP_009305694.1	ANK repeat	7..36	CDD:293786
		Ank_2	9..102	CDD:289560
		ANK	39..159	CDD:238125
		ANK repeat	39..69	CDD:293786
		ANK repeat	71..102	CDD:293786
		Ank_2	76..162	CDD:289560
		ANK repeat	138..170	CDD:293786
		Ank_4	139..192	CDD:290365
		zf-DHHC	384..509	CDD:279823	39/155 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900