DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sinah and siah1

DIOPT Version :9

Sequence 1:	NP_648927.1	Gene:	sinah / 39885	FlyBaseID:	FBgn0259794	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_005159200.1	Gene:	siah1 / 80955	ZFINID:	ZDB-GENE-010319-31	Length:	334	Species:	Danio rerio

Alignment Length:	293	Identity:	134/293 - (45%)
Similarity:	184/293 - (62%)	Gaps:	17/293 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VKRQSPDAAAAG--ELVPSRRKDSVAVQSGIVATGPLDTTRSGARDDFLMALLECPVCFGYIMPP 116
            :.||:..|...|  :..||:|   |...||        ||.|.:.   |.:|.||||||.|::||
Zfish    53 MSRQTATALPTGTSKCPPSQR---VPTLSG--------TTASNSD---LASLFECPVCFDYVLPP 103

  Fly   117 IMQCPRGHLICSTCRSKLTICPVCRVFMTNIRSLAMEKVASKLIFPCKHSHFGCRARLSYAEKTK 181
            |:||..|||:||.||.|||.||.||..:.:||:|||||||:.::||||::..||...|.:.:|.:
Zfish   104 ILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAE 168

  Fly   182 HEEDCECRPYFCPYPDDKCSWQGPLRDVYQHLMSSHENVITMEGNDIIFLATNVNLEGALDWTMV 246
            |||.||.|||.||.|...|.|||.|..|..||:..|:::.|::|.||:||||::||.||:||.|:
Zfish   169 HEELCEFRPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMM 233

  Fly   247 QSCHGRHFLLSLEKINLGEDCQQYFTACRMIGSMKDAAEFVYNISLEAYNRTLRWQSKPRSIREN 311
            |||.|.||:|.|||....:..||:|...::||:.|.|..|.|.:.|..:.|.|.|::.||||.|.
Zfish   234 QSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEG 298

  Fly   312 F-SSFTNADFLVLNKHTVELFSEDGNLALNVVI 343
            . ::..|:|.||.:....:||:|:|||.:||.|
Zfish   299 IATAIMNSDCLVFDTSIAQLFAENGNLGINVTI 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sinah	NP_648927.1	zf-C3HC4	106..140	CDD:278524	23/33 (70%)
sinah	NP_648927.1	Sina	147..341	CDD:281181	90/194 (46%)
siah1	XP_005159200.1	Sina	134..330	CDD:281181	91/195 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3002
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60089
OrthoDB	1	1.010	-	-		D780610at2759
OrthoFinder	1	1.000	-	-		FOG0001170
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104798
Panther	1	1.100	-	-	O	PTHR45877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X796
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.790