Protein Alignment sinah and ZFTRAF1

DIOPT Version :10

• Sequence 1: NP_648927.1
• Gene: sinah / 39885
• FlyBaseID: FBgn0259794
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_001317547.1
• Gene: ZFTRAF1 / 50626
• HGNCID: 17806
• Length: 404
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 62/269 - (23%)
• Similarity: 100/269 - (37%)
• Gaps: 56/269 - (20%)

  Fly    14 ERVSPQRTIDTPTASGEMLTRRQSAPALVVPPEETTHVVVVKRQSPDAAAAGELVPSRRKDSVAV 78
            |...|....:...|....|..:::|.....||::..........:..|||||
Human    46 EAAGPGLPDEAGLAGARQLQLQEAAGDPDAPPKKRLRAAEAAEAAAAAAAAG------------- 97

  Fly    79 QSGIVATGPLDTTRSGARDDFLMALLECPVCFGYIMPPIMQCPRGHLICSTC----------RSK 133
                          ||..::.|.::|.|.||.......:.||..|||:|:.|          :.:
Human    98 --------------SGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADARLKEE 148

  Fly   134 LTICPVCRVFMTN---IRSLAMEKVASKLIFPCKHSHFGCRARLSYAEKTKHE-EDCECRPYFCP 194
            ...||.||..::.   .|:||:||..|:|...|..    |..:...:...:|: |:|:.|...|.
Human   149 QATCPNCRCEISKSLCCRNLAVEKAVSELPSECGF----CLRQFPRSLLERHQKEECQDRVTQCK 209

  Fly   195 YPDDKCSWQGPLRDVYQHLMSSHENVI---TMEGNDIIFLATNVNLEGALDWTMVQSCHGRHFLL 256
            |....|.|.||.     |.::.||...   |..|::::.:...::.....:..:..|...   ||
Human   210 YKRIGCPWHGPF-----HELTVHEAACAHPTKTGSELMEILDGMDQSHRKEMQLYNSIFS---LL 266

  Fly   257 SLEKINLGE 265
            |.|||...|
Human   267 SFEKIGYTE 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sinah	NP_648927.1	RING_Ubox	102..151	CDD:473075	16/61 (26%)
		Sina	147..341	CDD:460824	32/123 (26%)
ZFTRAF1	NP_001317547.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		RING-HC_CYHR1	100..161	CDD:438168	16/60 (27%)
		Sina	166..>227	CDD:460824	20/69 (29%)
		CYHR1_C	249..404	CDD:439370	8/30 (27%)