DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sinah and Trim50

DIOPT Version :9

Sequence 1:	NP_648927.1	Gene:	sinah / 39885	FlyBaseID:	FBgn0259794	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001333674.1	Gene:	Trim50 / 215061	MGIID:	2664992	Length:	484	Species:	Mus musculus

Alignment Length:	256	Identity:	53/256 - (20%)
Similarity:	89/256 - (34%)	Gaps:	66/256 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 LECPVCFGYIMPPIM-QCPRGHLICSTCRSKLT-------ICPVCRVFM---TNIRSLAMEKVAS 157
            |:||:|......|:| ||  ||..|..|...|:       .|||||..:   ::..::::.:|..
Mouse    14 LQCPICLEVFKEPLMLQC--GHSYCKDCLDNLSQHLDSELCCPVCRQSVDCSSSPPNVSLARVID 76

  Fly   158 KLIFP-------CKHSHFGCRARLS-YAEKTKHEEDCECRPYFCPYPDDKCSWQG--------PL 206
            .|..|       |.|.    |..|| :.||.:.        :.|    ..|...|        |:
Mouse    77 ALRLPGDIEPTVCVHH----RNPLSLFCEKDQE--------FIC----GLCGLLGSHQHHRVTPV 125

  Fly   207 RDVY-----------QHLMSSHENVITMEGNDIIFLATNVNLEGALDWTMVQSCHGRHFLLSLEK 260
            ..||           ..|...|.||....|..:......:|......|.:.:.....|.|:..||
Mouse   126 STVYSRMKEELAGRISELKEEHRNVEEHIGKLVNNRTRIINESDVFSWVIRREFQELHHLVDEEK 190

  Fly   261 INLGEDCQQYFTACRMIGSMKDAAEFVYNISLEAYNRTLRWQSKPRSIRENFSSFTNADFL 321
            ....|..:.:...  ::.|:        ::.||....|....::...:.|.|.:.::.:|:
Mouse   191 ARCLEGLEGHTRG--LVASL--------DMQLEQAQGTQERLAQAEQVLEQFGNESHHEFI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sinah	NP_648927.1	zf-C3HC4	106..140	CDD:278524	14/41 (34%)
sinah	NP_648927.1	Sina	147..341	CDD:281181	35/202 (17%)
Trim50	NP_001333674.1	RING-HC_TRIM50_like_C-IV	14..58	CDD:319519	17/45 (38%)
		RING-HC finger (C3HC4-type)	16..56	CDD:319519	14/41 (34%)
		Bbox_SF	88..125	CDD:381767	10/52 (19%)
		End3	<131..231	CDD:372297	16/109 (15%)
		SPRY_PRY_TRIM50	283..471	CDD:293977
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910