Protein Alignment sinah and Siah1a

DIOPT Version :10

• Sequence 1: NP_648927.1
• Gene: sinah / 39885
• FlyBaseID: FBgn0259794
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: XP_006530847.3
• Gene: Siah1a / 20437
• MGIID: 108064
• Length: 355
• Species: Mus musculus
• Alignment Length: 348
• Identity: 142/348 - (40%)
• Similarity: 204/348 - (58%)
• Gaps: 26/348 - (7%)

  Fly     1 MSVRNSRPQLSWPERVSPQRTIDTPTASGEMLTRRQSAPALVVPPEETTHVVV--VKRQSPDAAA 63
            :.:|:|...|..|.    ...:.||.|:.:.|...:....|   |...:::..  :.||:..|..
Mouse    26 LPLRDSSGSLQAPR----CNLVCTPWAAADRLFLERYRICL---PWHKSYICAFEMSRQTATALP 83

  Fly    64 AG--ELVPSRRKDSVAVQSGIVATGPLDTTRSGARDDFLMALLECPVCFGYIMPPIMQCPRGHLI 126
            .|  :..||:|..::              |.:.|.::.|.:|.||||||.|::|||:||..|||:
Mouse    84 TGTSKCPPSQRVPAL--------------TGTTASNNDLASLFECPVCFDYVLPPILQCQSGHLV 134

  Fly   127 CSTCRSKLTICPVCRVFMTNIRSLAMEKVASKLIFPCKHSHFGCRARLSYAEKTKHEEDCECRPY 191
            ||.||.|||.||.||..:.:||:|||||||:.::||||::..||...|.:.||.:|||.||.|||
Mouse   135 CSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEITLPHTEKAEHEELCEFRPY 199

  Fly   192 FCPYPDDKCSWQGPLRDVYQHLMSSHENVITMEGNDIIFLATNVNLEGALDWTMVQSCHGRHFLL 256
            .||.|...|.|||.|..|..|||..|:::.|::|.||:||||::||.||:||.|:|||.|.||:|
Mouse   200 SCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFML 264

  Fly   257 SLEKINLGEDCQQYFTACRMIGSMKDAAEFVYNISLEAYNRTLRWQSKPRSIRENF-SSFTNADF 320
            .|||....:..||:|...::||:.|.|..|.|.:.|..:.|.|.|::.||||.|.. ::..|:|.
Mouse   265 VLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDC 329

  Fly   321 LVLNKHTVELFSEDGNLALNVVI 343
            ||.:....:||:|:|||.:||.|
Mouse   330 LVFDTSIAQLFAENGNLGINVTI 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sinah	NP_648927.1	RING_Ubox	102..151	CDD:473075	29/48 (60%)
		Sina	147..341	CDD:460824	92/194 (47%)
Siah1a	XP_006530847.3	RING_Ubox	109..159	CDD:473075	29/49 (59%)
		Sina	155..351	CDD:460824	93/195 (48%)