DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sinah and mes-4

DIOPT Version :9

Sequence 1:	NP_648927.1	Gene:	sinah / 39885	FlyBaseID:	FBgn0259794	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_506333.1	Gene:	mes-4 / 179824	WormBaseID:	WBGene00003222	Length:	898	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	47/193 - (24%)
Similarity:	73/193 - (37%)	Gaps:	48/193 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 RSKLTICPVCRVFM-TNIRS---LAMEKVA-SKLIF---PCKHSHFGCRARLSYAEKTKHEEDCE 187
            ::.:|:.|...|.| ::|::   :..||.: ||.|.   .|:..|.|||...:...|...::.||
Worm   286 KNAVTVVPKADVTMKSHIKACCVIGCEKSSNSKTIMCKTCCRSFHSGCREVETLNGKPIPDDQCE 350

  Fly   188 CRPYFCPYPD---------DKCSWQGPLRDVYQHLMSSHENVITMEGNDIIFLATNVNLEGALDW 243
            ......|.|.         |...|.....|.|::          ..||     ..|:|.| .|.:
Worm   351 SCVCGDPIPQNTLILAKWTDNSFWLALTLDWYKY----------PTGN-----RGNINFE-RLGY 399

  Fly   244 TMVQSCHGRHFLLSLEKINLGEDCQQYFTACRMIGSMKDAAEFVYNISLEAYNRTLR--WQSK 304
            |:||      :|:..|.   .::.|...:    |..:.|.|....|....|.|.|||  |:.|
Worm   400 TVVQ------WLIPQEN---DKEKQPLMS----IVPVSDIARLTKNYFSLAKNSTLRNLWEEK 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sinah	NP_648927.1	zf-C3HC4	106..140	CDD:278524	2/8 (25%)
sinah	NP_648927.1	Sina	147..341	CDD:281181	43/176 (24%)
mes-4	NP_506333.1	PHD_SF	207..269	CDD:304600
mes-4	NP_506333.1	SET	537..671	CDD:214614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S11711
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950