Protein Alignment sina and siah1

DIOPT Version :10

• Sequence 1: NP_476725.1
• Gene: sina / 39884
• FlyBaseID: FBgn0003410
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_005159200.1
• Gene: siah1 / 80955
• ZFINID: ZDB-GENE-010319-31
• Length: 334
• Species: Danio rerio
• Alignment Length: 288
• Identity: 215/288 - (74%)
• Similarity: 240/288 - (83%)
• Gaps: 11/288 - (3%)

  Fly    26 TNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSG 90
            |.|:..||:|....:....|.|.:::|           ::||.|||||||||||||||||||.||
Zfish    57 TATALPTGTSKCPPSQRVPTLSGTTAS-----------NSDLASLFECPVCFDYVLPPILQCQSG 110

  Fly    91 HLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCEC 155
            ||||.:||.||||||||||||.:||||||||||::|.||||::..||..:|.:|:|.||||.||.
Zfish   111 HLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAEHEELCEF 175

  Fly   156 RPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHH 220
            |||.||||||||||||.||.||.||:..|||||||||||||||||||||||||||||||||||.|
Zfish   176 RPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFH 240

  Fly   221 FMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHN 285
            |||||||||||||||||||||||||:||:||||.|||||||:||||||||.|||||||:|:||.|
Zfish   241 FMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMN 305

  Fly   286 SDCLVFDTSIAQLFADNGNLGINVTISL 313
            |||||||||||||||:|||||||||||:
Zfish   306 SDCLVFDTSIAQLFAENGNLGINVTISM 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sina	NP_476725.1	RING_Ubox	68..118	CDD:473075	42/49 (86%)
		Sina	114..310	CDD:460824	162/195 (83%)
siah1	XP_005159200.1	RING-HC_SIAH2	88..138	CDD:438410	42/49 (86%)
		Sina	134..330	CDD:460824	162/195 (83%)