Protein Alignment sina and Siah3

DIOPT Version :10

• Sequence 1: NP_476725.1
• Gene: sina / 39884
• FlyBaseID: FBgn0003410
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001178047.1
• Gene: Siah3 / 692004
• RGDID: 1592168
• Length: 268
• Species: Rattus norvegicus
• Alignment Length: 261
• Identity: 107/261 - (40%)
• Similarity: 144/261 - (55%)
• Gaps: 35/261 - (13%)

  Fly    76 CFDYVLPPI-----------LQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKF- 128
            ||..||..|           :..::|.||||       ..||......:.|....:..|....|
  Rat     7 CFGAVLDLIHLRFQHYKAKRVFSAAGQLVCV-------VNPTNNLKYVSSRRAITQNSAEQGSFH 64

  Fly   129 ----PCKHSGYGCTASLVYTEKTEHE--------ETCECRPYLCPCPGASCKWQGPLDLVMQHLM 181
                | .|..:.|..:.:|.....|.        .:.:..|  |.||..||:|:|.|::|:.||.
  Rat    65 QHHLP-HHHRHHCHHNHLYQHARPHHLHHQEPGLHSTQMTP--CICPLFSCQWEGHLEVVVPHLR 126

  Fly   182 MSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGS 246
            ..|: |..|.|.:|||||||::||...||::|.||.||||:|||.|||:::||.||||.:.|||:
  Rat   127 QIHR-IDILHGAEIVFLATDMHLPAPADWIIMHSCLGHHFLLVLRKQERHEGHPQFFATMMLIGT 190

  Fly   247 RKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTI 311
            ..:|:.|.||||||.|.|||.|||.|||:.|.|.|.|.:.||||.:||:||||:|||:|.|.:.|
  Rat   191 PTQADCFTYRLELNRNHRRLKWEATPRSVLECVDSVITDGDCLVLNTSLAQLFSDNGSLAIGIAI 255

  Fly   312 S 312
            :
  Rat   256 T 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sina	NP_476725.1	RING_Ubox	68..118	CDD:473075	13/52 (25%)
		Sina	114..310	CDD:460824	94/208 (45%)
Siah3	NP_001178047.1	Sina	131..256	CDD:239753	73/124 (59%)