Protein Alignment sina and siah1

DIOPT Version :9

• Sequence 1: NP_001287089.1
• Gene: sina / 39884
• FlyBaseID: FBgn0003410
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: XP_012816483.1
• Gene: siah1 / 548553
• XenbaseID: XB-GENE-1014415
• Length: 313
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 222/312 - (71%)
• Similarity: 244/312 - (78%)
• Gaps: 28/312 - (8%)

  Fly     6 NPKRREPTAAAAGAGATGVATNTSTSTGS----SSAGNTSSANTSSSSSSSLSSAGGGDAGMSAD 66
            :||||:..:...   ||.:.|.||....|    :..|.|:|.|                     |
 Frog    25 DPKRRKEMSRQT---ATAIPTGTSKCPPSQRVPALTGTTASNN---------------------D 65

  Fly    67 LTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCK 131
            |.|||||||||||||||||||.||||||.:||.||||||||||||.:||||||||||::|.||||
 Frog    66 LASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCK 130

  Fly   132 HSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIV 196
            ::..||..:|.:|||.:|||.||.|||.||||||||||||.||.||.|||..|||||||||||||
 Frog   131 YASSGCEVTLPHTEKADHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLMHQHKSITTLQGEDIV 195

  Fly   197 FLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNG 261
            ||||||||||||||||||||||.||||||||||||||||||||||||||:||:||||.|||||||
 Frog   196 FLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNG 260

  Fly   262 NRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISL 313
            :||||||||.|||||||:|:||.||||||||||||||||:|||||||||||:
 Frog   261 HRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISM 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sina	NP_001287089.1	Sina	114..310	CDD:281181	163/195 (84%)
siah1	XP_012816483.1	RING-HC_SIAH1	70..109	CDD:319665	34/38 (89%)
		RING-HC finger (C3HC4-type)	72..106	CDD:319665	29/33 (88%)
		Sina	113..309	CDD:367355	163/195 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	348	1.000	Domainoid score	I1028
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20654
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1589
OMA	1	1.010	-	-		QHG60089
OrthoDB	1	1.010	-	-		D780610at2759
OrthoFinder	1	1.000	-	-		FOG0001170
OrthoInspector	1	1.000	-	-		otm48831
Panther	1	1.100	-	-	LDO	PTHR45877
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2793
SonicParanoid	1	1.000	-	-		X796
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110