Protein Alignment sina and ZFTRAF1

DIOPT Version :10

• Sequence 1: NP_476725.1
• Gene: sina / 39884
• FlyBaseID: FBgn0003410
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_001317547.1
• Gene: ZFTRAF1 / 50626
• HGNCID: 17806
• Length: 404
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 57/270 - (21%)
• Similarity: 98/270 - (36%)
• Gaps: 65/270 - (24%)

  Fly    12 PTAAAAGAGATGVATNTSTSTGSSSAGNTSSA--------------------------------- 43
            |.|..||:...||........| ::||..::|
Human    12 PAAGPAGSVPAGVGVGVGAGPG-AAAGQAAAAALGEAAGPGLPDEAGLAGARQLQLQEAAGDPDA 75

  Fly    44 ------NTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSC----- 97
                  ..:.::.::.::|..|...:...|.|:..|.||.|.....:.||::|||:|..|
Human    76 PPKKRLRAAEAAEAAAAAAAAGSGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLL 140

  Fly    98 -----RSKLTCCPTCRGPLAN---IRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHE-ETC 153
                 :.:...||.||..::.   .||||:||..|.:...|   |: |......:....|: |.|
Human   141 ADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSEC---GF-CLRQFPRSLLERHQKEEC 201

  Fly   154 ECRPYLCPCPGASCKWQGPL-DLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCF 217
            :.|...|......|.|.||. :|.:.....:|.:.|   |.:::.:...::.....:..:..|.|
Human   202 QDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKT---GSELMEILDGMDQSHRKEMQLYNSIF 263

  Fly   218 GHHFMLVLEK 227
            .   :|..||
Human   264 S---LLSFEK 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sina	NP_476725.1	RING_Ubox	68..118	CDD:473075	18/62 (29%)
		Sina	114..310	CDD:460824	28/116 (24%)
ZFTRAF1	NP_001317547.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/9 (44%)
		RING-HC_CYHR1	100..161	CDD:438168	17/60 (28%)
		Sina	166..>227	CDD:460824	20/64 (31%)
		CYHR1_C	249..404	CDD:439370	5/25 (20%)