Protein Alignment sina and siah-1

DIOPT Version :10

• Sequence 1: NP_476725.1
• Gene: sina / 39884
• FlyBaseID: FBgn0003410
• Length: 314
• Species: Drosophila melanogaster
• Sequence 2: NP_500409.1
• Gene: siah-1 / 177138
• WormBaseID: WBGene00021369
• Length: 419
• Species: Caenorhabditis elegans
• Alignment Length: 313
• Identity: 195/313 - (62%)
• Similarity: 234/313 - (74%)
• Gaps: 11/313 - (3%)

  Fly    12 PTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSA-----GGGDA--GMSADLTS 69
            |.:|.:....|.|...|.....|:..|:... ||::::....|.|     |||.|  ..||::.|
 Worm    89 PPSAVSTISGTAVLGKTMARVQSNPPGSIPH-NTTTTAQGIQSVAPHIPIGGGGATDDSSAEILS 152

  Fly    70 LFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSG 134
            :||||||.:|:|||.:|||||||||.:||.||.||||||||..::|||.:||:|:.|:||||.|.
 Worm   153 VFECPVCLEYMLPPYMQCSSGHLVCSNCRPKLQCCPTCRGPTPSVRNLGLEKIANTVRFPCKFST 217

  Fly   135 YGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLA 199
            .||..:..:.:||||||.||.|||.||||||||||||.|..||:||...||||||||||||||||
 Worm   218 SGCPLNFHHADKTEHEELCEFRPYCCPCPGASCKWQGGLSDVMEHLKKIHKSITTLQGEDIVFLA 282

  Fly   200 TDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYD---GHQQFFAIVQLIGSRKEAENFVYRLELNG 261
            ||||||||||||||||||.::||||||||||||   ..|.|:|:||||||:|||:||||||||:.
 Worm   283 TDINLPGAVDWVMMQSCFDYNFMLVLEKQEKYDPAQPTQMFYAVVQLIGSKKEADNFVYRLELSA 347

  Fly   262 NRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV 314
            :|||::|||.||||||||..||..||||.||::.|||||:|||||||||||.:
 Worm   348 SRRRMSWEATPRSIHEGVVVAIQQSDCLAFDSNAAQLFAENGNLGINVTISRI 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sina	NP_476725.1	RING_Ubox	68..118	CDD:473075	34/49 (69%)
		Sina	114..310	CDD:460824	142/198 (72%)
siah-1	NP_500409.1	RING-HC_SIAH1	149..193	CDD:438409	30/43 (70%)
		Sina	197..396	CDD:460824	142/198 (72%)