DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TSG101 and Uevld

DIOPT Version :9

Sequence 1:	NP_524120.1	Gene:	TSG101 / 39881	FlyBaseID:	FBgn0036666	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001035785.1	Gene:	Uevld / 54122	MGIID:	1860490	Length:	471	Species:	Mus musculus

Alignment Length:	184	Identity:	66/184 - (35%)
Similarity:	97/184 - (52%)	Gaps:	10/184 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ITKYLSKYKYVAATKKDVVDVVTSFRSLTYDLQRFVFNDGSSKELFTIQGTIPVVYKNNTYYIPI 73
            :.:.|.|||:...|.:::.:|..||....|.:..:||.|.|.|:|....|||||:|:..||.|||
Mouse     8 VRRLLGKYKFRDLTVEELKNVSVSFPHFRYSVDTYVFKDTSQKDLLNFTGTIPVMYQGKTYNIPI 72

  Fly    74 CIWLMDTHPQNAPMCFVKPTPTMQIKVSMYVDHNGKVYLPYLHDWQPHSSDLLSLIQVMIVTFGD 138
            ..|::|:||...|:||:|||..|:|.|..:||..|::|||||.:|....|.::.||:.||..|.:
Mouse    73 RFWILDSHPFAPPICFLKPTANMEISVGKHVDAKGRIYLPYLQNWSHPKSAIVGLIKEMIAKFQE 137

  Fly   139 HPPVYSKPKEQIAAPYPTNSYMPQ----------PGAPGGSNSFLPYPTAGGAG 182
            ..|:||.|....|......:|:.:          .|.....|..|...|..|:|
Mouse   138 ELPLYSIPSSNEAQQVDLLAYITKITEGVSDINSRGWTNHENKILNKITVVGSG 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TSG101	NP_524120.1	UEV	22..140	CDD:283415	50/117 (43%)
		ARS2	<149..227	CDD:282772	8/44 (18%)
		TBPIP	<242..353	CDD:284512
		Vps23_core	336..393	CDD:286532
Uevld	NP_001035785.1	UEV	21..138	CDD:283415	50/116 (43%)
		PLN02602	177..471	CDD:178212	5/15 (33%)
		NADB_Rossmann	183..468	CDD:304358	3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2391
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435538at2759
OrthoFinder	1	1.000	-	-		FOG0001267
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920