Protein Alignment TSG101 and uevld

DIOPT Version :9

• Sequence 1: NP_524120.1
• Gene: TSG101 / 39881
• FlyBaseID: FBgn0036666
• Length: 408
• Species: Drosophila melanogaster
• Sequence 2: NP_001007958.1
• Gene: uevld / 493332
• XenbaseID: XB-GENE-5786365
• Length: 476
• Species: Xenopus tropicalis
• Alignment Length: 447
• Identity: 117/447 - (26%)
• Similarity: 187/447 - (41%)
• Gaps: 94/447 - (21%)

  Fly     9 ITKYLSKYKYVAATKKDVVDVVTSFRSLTYDLQRFVFNDGSSKELFTIQGTIPVVYKNNTYYIPI 73
            :.:.|.|||:...|.:::.|:..:|.|..:.::.:.|.|||.|:|..:.||:|:.::..||.|||
 Frog     8 LRQQLGKYKFRDLTIEELKDLNRTFPSFIFSMETYTFRDGSQKDLLNLTGTVPMKHQGTTYNIPI 72

  Fly    74 CIWLMDTHPQNAPMCFVKPTPTMQIKVSMYVDHNGKVYLPYLHDWQPHSSDLLSLIQVMIVTFGD 138
            |:|::|:||...|:||:||:..|.|:|..::|..|::|||||.:|....|.:..||:.|.|.|.:
 Frog    73 CLWILDSHPFAPPLCFLKPSGNMGIRVGRHIDAQGRIYLPYLQNWSHPKSTVTGLIREMAVKFEE 137

  Fly   139 HPPVYSKPKEQIAAPYPTNSYMPQ---------PGAP--------GGSNSFLPYPTAGGAGGSNF 186
            ..|:||...|..|......||:.|         ..||        ||.:..|....|..|.|
 Frog   138 ELPLYSLSAEDGARQRELLSYIAQVTDGVSSMDVKAPSRAKVTVIGGGDMALACLLAVSAKG--- 199

  Fly   187 PPYPTGSNVGPYPPTPAGPAGGSGYP----AYPNFIQPT------AGGYPPAAGYNP-SNPSSTG 240
                |...:....||....|||:...    :.|| :|.|      ||........|. ||..|..
 Frog   200 ----TAGKLLLLDPTDGEAAGGAAADLEIFSLPN-VQVTKDFSAIAGSAIVIVTVNSWSNSQSYV 259

  Fly   241 TITEEHIK--ASIISAIDDKLRRRVQEKVNQYQAEIETLNRTKQELLEG--------------SA 289
            .:.:.:::  ..|:.|:.....:.:....:| ..||.|....|   |.|              |.
 Frog   260 GVLQSNVELLRGILPAVAHHCPKCLLLVASQ-PVEIMTYATWK---LSGFPHNRVLGIGCNLDSG 320

  Fly   290 KIDAIIERLEREHIDMQKNISILKDKEQELEKAL---EDLESAEAI--NPDEAVTTTAP--LYRQ 347
            :...:||:              |.|.|:..:.|.   |..::..|:  .||.:.....|  ||.:
 Frog   321 RFRHVIEK--------------LADSEEGAQGAWIIGEQSDNKVAVWGAPDSSANRQTPCKLYPK 371

  Fly   348 LLNAYADEAATEDAIYYL-GEGLRGGVIDL------ETFLKH------VRQLSRKQF 391
            :.    .|..|..|:..| |:|.|...:.|      :|.:::      |..|.:.||
 Frog   372 IF----QEQLTSRALEILKGKGQRSWSVGLSVADITDTLVQNKGKVHSVSALCKGQF 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSG101	NP_524120.1	UEV	22..140	CDD:283415	45/117 (38%)
		ARS2	<149..227	CDD:282772	24/104 (23%)
		TBPIP	<242..353	CDD:284512	23/133 (17%)
		Vps23_core	336..393	CDD:286532	16/71 (23%)
uevld	NP_001007958.1	UEV	21..138	CDD:283415	45/116 (39%)
		PLN02602	166..476	CDD:178212	60/289 (21%)
		NADB_Rossmann	174..473	CDD:304358	59/281 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435538at2759
OrthoFinder	1	1.000	-	-		FOG0001267
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020