DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nudC and nud-1

DIOPT Version :9

Sequence 1:	NP_001246805.1	Gene:	nudC / 39879	FlyBaseID:	FBgn0021768	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_499749.1	Gene:	nud-1 / 176754	WormBaseID:	WBGene00003829	Length:	320	Species:	Caenorhabditis elegans

Alignment Length:	325	Identity:	153/325 - (47%)
Similarity:	219/325 - (67%)	Gaps:	13/325 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KFDNILLAVAEKHHGGVPEFLGTLASFLRRKTDFFTGAKQTEWEKLLLDVFNKESKLAVTENYEK 71
            :||::||::|::..|||||.|..|..||.|||||::||...:...|||:.|:|....|:.|..|.
Worm     6 RFDSVLLSMAQQLSGGVPEMLDVLFEFLSRKTDFYSGAGVDQARTLLLEKFDKHGGKAMKEAEEA 70

  Fly    72 IKAREASQRLKAEKERAERKARKQEIDDNKICDITDEEAAAIIKEEETKKRQQLLDSAGGEPSAS 136
            .|.:|..:|..||:..|::...::|..:.|:.::|||||||..||:.....:.|      |....
Worm    71 KKRKEEQERKLAERRAAQKAKEEEEFRNAKVVEVTDEEAAAFEKEQAKNSVENL------EKFVD 129

  Fly   137 NRDGISKPIEKVDDESDKSELGKLM-PNAGNGCTLENYTWTQTLEEVELKIPFNLTFGLRARDLV 200
            |....||..|..|::|      ||| ||:|||..|..|.|||||:|:|:|||....|.:::||:|
Worm   130 NEGETSKDAEVEDEDS------KLMKPNSGNGADLAKYQWTQTLQELEVKIPIAAGFAIKSRDVV 188

  Fly   201 ISIGKKSLKVGIKGQTPIIDGELCGEVKTEESVWVLQDSKTVMITLDKINKMNWWSRLVTTDPEI 265
            :.|.|.|:.||:|.|.||:||:|...:|.|...||:::.|.:::||:|||.|.||:|.:.:||.|
Worm   189 VKIEKTSVSVGLKNQAPIVDGKLPHAIKVENCNWVIENGKAIVLTLEKINDMEWWNRFLDSDPPI 253

  Fly   266 STRKINPESSKLSDLDGETRSMVEKMMYDQRQKELGLPTSEDRKKQDILEKFKQQHPEMDFSKCK 330
            :|:::.||:|||||||||||:|||||||||||||:|||||:::||.|:|::|.:||||||||..|
Worm   254 NTKEVKPENSKLSDLDGETRAMVEKMMYDQRQKEMGLPTSDEKKKHDMLQQFMKQHPEMDFSNAK 318

Fly 331 330
Worm 319 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nudC	NP_001246805.1	Nudc_N	7..58	CDD:290757	24/50 (48%)
nudC	NP_001246805.1	p23_mNUDC_like	173..259	CDD:107241	41/85 (48%)
nud-1	NP_499749.1	Nudc_N	6..>40	CDD:372893	18/33 (55%)
		PTZ00121	<54..>174	CDD:173412	47/131 (36%)
		p23_mNUDC_like	161..247	CDD:107241	41/85 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161296
Domainoid	1	1.000	128	1.000	Domainoid score	I3305
eggNOG	1	0.900	-	-		E1_KOG2265
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4812
Inparanoid	1	1.050	304	1.000	Inparanoid score	I1600
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56463
OrthoDB	1	1.010	-	-		D1474731at2759
OrthoFinder	1	1.000	-	-		FOG0003931
OrthoInspector	1	1.000	-	-		oto19525
orthoMCL	1	0.900	-	-		OOG6_102007
Panther	1	1.100	-	-	LDO	PTHR12356
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R854
SonicParanoid	1	1.000	-	-		X2707
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840