DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9674 and preT

DIOPT Version :9

Sequence 1:	NP_001246804.1	Gene:	CG9674 / 39878	FlyBaseID:	FBgn0036663	Length:	2115	Species:	Drosophila melanogaster
Sequence 2:	NP_416651.1	Gene:	preT / 949049	ECOCYCID:	G7145	Length:	412	Species:	Escherichia coli

Alignment Length:	448	Identity:	130/448 - (29%)
Similarity:	194/448 - (43%)	Gaps:	71/448 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1663 QAARCMECGVPFCQSNSTGCPLGNIIPKWNDLVFHGEWQEALRQLLQTNNFPEFTGRVCPAP--C 1725
            :|:||:.|....|   |..||......|:...::...::.|...:.:.|.......||||..  |
E. coli    22 EASRCLLCHDAPC---SQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLC 83

  Fly  1726 EGSCV-LGISEPAVTIKNIECAIIDHAFEQGWIKPEI--PEVRTGKRVAIVGSGPSGLAASQQLN 1787
            :..|. .|:..| :.|..::..:.|...:.|.   ||  |..:|..:|||:|:||:||.||..|.
E. coli    84 QSGCTRAGVDAP-IDIGRLQRFVTDFEQQTGM---EIYQPGTKTLGKVAIIGAGPAGLQASVTLT 144

  Fly  1788 RAGHFVTVFERNDRVGGLLQYGIPTMKLSKEVVKRRVDLMADEGIEFRTNVHVGKDLKAEQLLQE 1852
            ..|:.||::|:....||.|:.|||..:|.:.|:...:..:...|:..:.|..||..|..|||..|
E. coli   145 NQGYDVTIYEKEAHPGGWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAE 209

  Fly  1853 YDAVLLTTGSTWPRDLPLANRDLKGIHFAMEFLEAQQKKQLGGKNDIISAAGKNVIIIGGGDTGC 1917
            ..|||:|.|.:....|||...  ..:..|::||  |:.:|..|...|..:|    :||||||...
E. coli   210 NRAVLVTVGLSSGSGLPLFEH--SDVEIAVDFL--QRARQAQGDISIPQSA----LIIGGGDVAM 266

  Fly  1918 DCIATSLRQGAKSITTFEILPEPPQKRAQDNPWPQWPKVFRVDYGHEEVKLKWGKDPRQYCTTTK 1982
            |..:|....|.:::|.                           ...||:.        ::..:.|
E. coli   267 DVASTLKVLGCQAVTC---------------------------VAREELD--------EFPASEK 296

  Fly  1983 EFVG--ENGA--IKGVNTVEVEWTKTETGQWRMQEVAGSEKYFPADLILLAMGFLGPEKTVPSEL 2043
            ||..  |.|.  |.|...|.||..|......|:    ..|....||.|:||:|     :....:.
E. coli   297 EFTSARELGVSIIDGFTPVAVEGNKVTFKHVRL----SGELTMAADKIILAVG-----QHARLDA 352

  Fly  2044 GLELDP-RGNIKASNGQYGTSNSKVFAAGDCRRGQSLVVWAITEGRQAARQVDSYLTG 2100
            ..||:| |..||..|  |.|.:.:||||||...|...||:|:..|::||..:..||.|
E. coli   353 FAELEPQRNTIKTQN--YQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAEAIHHYLEG 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9674	NP_001246804.1	gltB	75..1565	CDD:236968
		GATase_2	88..504	CDD:278726
		Glu_syn_central	543..828	CDD:282720
		GltS_FMN	918..1271	CDD:239202
		gltB_C	1316..1565	CDD:238482
		gltD	1623..2106	CDD:237213	130/448 (29%)
		Fer4_8	1645..1756	CDD:302761	21/95 (22%)
		NAD_binding_8	1772..>1804	CDD:290186	13/31 (42%)
preT	NP_416651.1	PRK11749	3..412	CDD:236967	130/448 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	0.910