|
Fly 29 SDNFD---SSAIGGSGDNFEESNELHLNGQQDQDVQEEQQQQMPWE--APGKQGLYDPQNEHEAC 88
||||| .:..||:..|:.:.:.||.: |. .|.|:|||||..||:||
Yeast 6 SDNFDPLEEAYEGGTIQNYNDEHHLHKS----------------WANVIPDKRGLYDPDYEHDAC 54
Fly 89 GVGFIVAIDGKRSHKILRDAQTLSERMNHRGACACDNDTGDGAGVLASIPHGLYSKALAKQ-GVT 152
||||:....|::||||:.||:.|...|.||||.:.|.: |||||:|..|||....:..... .:.
Yeast 55 GVGFVANKHGEQSHKIVTDARYLLVNMTHRGAVSSDGN-GDGAGILLGIPHEFMKREFKLDLDLD 118
Fly 153 LPELGDYATG-IFYLDEAQH-----AAAEKEFDDLAKSLGLEVIAWRTVPSNQSAIGVVARKSEP 211
:||:|.||.| :|:....:: ...:|.|:|||.|..|.|:.||.||.:.:.:|.||...||
Yeast 119 IPEMGKYAVGNVFFKKNEKNNKKNLIKCQKIFEDLAASFNLSVLGWRNVPVDSTILGDVALSREP 183
Fly 212 LSRQVFV------RRPAGSDEKAFERQVFVLRKRASHELIKPGRR--FYICSLSDRTVVYKGLFT 268
...|..: ::|..::.| |..|:::|||.||.:: |.. ||:|||::.|:||||..|
Yeast 184 TILQPLLVPLYDEKQPEFNETK-FRTQLYLLRKEASLQI---GLENWFYVCSLNNTTIVYKGQLT 244
Fly 269 SDQLWDYYTDLKDPEFETYLALVHTRFSTNTFPSWERAHPLRVLAHNGEINTLRGNVNLMKAREG 333
..|:::||.||.:..|::::||||:||||||||||:||.|||.|||||||||||||.|.|::|||
Yeast 245 PAQVYNYYPDLTNAHFKSHMALVHSRFSTNTFPSWDRAQPLRWLAHNGEINTLRGNKNWMRSREG 309
Fly 334 VMQSDLFGDQLKKLYPVVEPNLSDSGSFDCVLEFLTMASDRSLPESVMTMVPEAWQNDKTMPQEK 398
||.|..|.|:|.||||::|...|||.:.|.|||.||:....||||:||.|||||:..| |..:.
Yeast 310 VMNSATFKDELDKLYPIIEEGGSDSAALDNVLELLTINGTLSLPEAVMMMVPEAYHKD--MDSDL 372
Fly 399 RDFYQWAACVMEPWDGPALISFTDGRYIGAVLDRNGLRPSRFYVTKENVLVMASEVGVYDVDPSQ 463
:.:|.||||:|||||||||::||||||.||:||||||||.|:|:|.::.::.||||||..::.|.
Yeast 373 KAWYDWAACLMEPWDGPALLTFTDGRYCGAILDRNGLRPCRYYITSDDRVICASEVGVIPIENSL 437
Fly 464 VTLKSRLKPGRMLLVDTKEKKLIQDIELKAKIAKSRPHSEWLQQKMITLDEI--RNANVLNTPPV 526
|..|.:||||.:.||||:..:::...:||::|:|.:....|| .|:|.||:: :.||:: |.
Yeast 438 VVQKGKLKPGDLFLVDTQLGEMVDTKKLKSQISKRQDFKSWL-SKVIKLDDLLSKTANLV---PK 498
Fly 527 DELAKLPASERGIFDPRLSLFGYSTETVNMLLIPMFKNKKEALGSMGNDAPLACLSNFQPIPYEY 591
:.:::...|.:...||||...||:.|.|..||.||....||||||||||||||||:....:.|:|
Yeast 499 EFISQDSLSLKVQSDPRLLANGYTFEQVTFLLTPMALTGKEALGSMGNDAPLACLNENPVLLYDY 563
Fly 592 FKQLFAQVTNPPIDPFREKVVMSMQCPLGPEANLLQPSAQQVHRIWLTNPILSIPDTQLLK--RN 654
|:|||||||||||||.||..|||::|.:||:.|||:..:.|..|:.|.:|||...:.|.|| ..
Yeast 564 FRQLFAQVTNPPIDPIREANVMSLECYVGPQGNLLEMHSSQCDRLLLKSPILHWNEFQALKNIEA 628
Fly 655 THRGWRTKVLDITFQYNEGVQGYIDAIDRICREGYAAAQAGYQLLVISDRGAGIDGKVAVSALLA 719
.:..|....:||||..:||:.||.|.||:|.:....|...|.::|:|:||..|.: :|::|:|:|
Yeast 629 AYPSWSVAEIDITFDKSEGLLGYTDTIDKITKLASEAIDDGKKILIITDRKMGAN-RVSISSLIA 692
Fly 720 LGALHHHLIETLQRMKVGIVVETAEAREVHHICVLLGYGADAICPYLAFELAQALRDDGVIAPEV 784
:..:|||||...||.:|.:::||.||||:||.|||||||.|.:.||||.|....:..:|::....
Yeast 693 ISCIHHHLIRNKQRSQVALILETGEAREIHHFCVLLGYGCDGVYPYLAMETLVRMNREGLLRNVN 757
Fly 785 NDK------QIYAAYAQAIDTGIAKVMAKMGISTLQSYKSAQIFEAVGLGSDLVAKCFRGTQSRI 843
||. ||...|..|||.||.|||:|||||||.|||.||||||:||.:.:|..||.||.|||
Yeast 758 NDNDTLEEGQILENYKHAIDAGILKVMSKMGISTLASYKGAQIFEALGLDNSIVDLCFTGTSSRI 822
Fly 844 GGVTLEILAKEGLQRYQLTYGKATPDTRILRNP--GQYHWRHGGEAHINEPSSIGSLQEAAVNKN 906
.|||.|.||::....::..|......::.:..| |:||:|.||..|:|||::|.|||:...|||
Yeast 823 RGVTFEYLAQDAFSLHERGYPSRQTISKSVNLPESGEYHFRDGGYKHVNEPTAIASLQDTVRNKN 887
Fly 907 LDAFEAFKKTTLDSVKKCALRGQLEFVTDRQ-SIDISEVEPASEIVKRFATGAMSFGSISLEAHQ 970
..:::.:.|..:::::.|.|||.||...:.. ||.:.:|||.:||.:|||:||||:||||:|||.
Yeast 888 DVSWQLYVKKEMEAIRDCTLRGLLELDFENSVSIPLEQVEPWTEIARRFASGAMSYGSISMEAHS 952
Fly 971 TLSITMNRIGGKSNTGEGGEDSDRYLNQDPNNSRRSAIKQVASGRFGVTASYLANADDLQIKMAQ 1035
||:|.|||:|.|||.||||||::|...|:..::.|||||||||.|||||:.||::||::|||:||
Yeast 953 TLAIAMNRLGAKSNCGEGGEDAERSAVQENGDTMRSAIKQVASARFGVTSYYLSDADEIQIKIAQ 1017
Fly 1036 GAKPGEGGELPGYKVTKDIAKTRKSVPGVGLISPPPHHDIYSIEDLAELIYDLKCSNPNARISVK 1100
|||||||||||.:||:|||||||.|.|.||||||||||||||||||.:|||||||:||.|.||||
Yeast 1018 GAKPGEGGELPAHKVSKDIAKTRHSTPNVGLISPPPHHDIYSIEDLKQLIYDLKCANPRAGISVK 1082
Fly 1101 LVSEVGVGVVASGVAKGKAEHIVISGHDGGTGASSWTGIKNAGLPWELGVAETHQVLVLNNLRSR 1165
||||||||:|||||||.||:||::|||||||||:.||.:|.||||||||:|||||.||||:||..
Yeast 1083 LVSEVGVGIVASGVAKAKADHILVSGHDGGTGAARWTSVKYAGLPWELGLAETHQTLVLNDLRRN 1147
Fly 1166 VIVQADGQLRTGFDVVVAALLGADEFGFSTAPLIVMGCTMMRKCHLNTCPVGIATQDPELRKKFT 1230
|:||.|||||||||:.||.||||:.|..:|.|||.|||.|:|:||||:|.||||||||.||.||.
Yeast 1148 VVVQTDGQLRTGFDIAVAVLLGAESFTLATVPLIAMGCVMLRRCHLNSCAVGIATQDPYLRSKFK 1212
Fly 1231 GKPEHVINFFFMLAEDIRKIMAGLGIRKFQDLIGRTDLLRVASQRDAKASNLDLKLLLQPALELR 1295
|:||||||||:.|.:|:|:|||.||.|...:::|.::.|:.....:|||.|:||..:|.||..:|
Yeast 1213 GQPEHVINFFYYLIQDLRQIMAKLGFRTIDEMVGHSEKLKKRDDVNAKAINIDLSPILTPAHVIR 1277
Fly 1296 PG--TNIVGGSVKQDFQLEKRSDNELIAKAQ-QIFSGADDNVTVKMRIHNEERAFGSTLSYHIAC 1357
|| |.. :.|||.:|..|.||:||.:|: .:..|...|:... |.|.:||.||||||.::.
Yeast 1278 PGVPTKF---TKKQDHKLHTRLDNKLIDEAEVTLDRGLPVNIDAS--IINTDRALGSTLSYRVSK 1337
Fly 1358 KYGEAGLPAGKSIDIFLEGSAGQSFCAFLARGVNVTLKGDANDYVGKGLCGGNVVIMPQDTVPFE 1422
|:||.|||. .::.:.:||||||||.||||.|:...|.|||||||||||.||.:||.|.....|:
Yeast 1338 KFGEDGLPK-DTVVVNIEGSAGQSFGAFLASGITFILNGDANDYVGKGLSGGIIVIKPPKDSKFK 1401
Fly 1423 SHLNVIVGNVCLYGATEGTAYFRGIASERFCVRNSGVTAVVEGV-GDHGCEYMTGGVVVILG-LT 1485
|..||||||.|.||||.|||:..|.|.|||.|||||.|.|||.: |::..||||||..::|. :.
Yeast 1402 SDENVIVGNTCFYGATSGTAFISGSAGERFGVRNSGATIVVERIKGNNAFEYMTGGRAIVLSQME 1466
Fly 1486 GRNFAAGMSGGIAYVYDLD-GSFKPKVNPESVELLPLEIEKDVLLVKELLADFIEKTGSKVAKEL 1549
..|..:|.:|||||....| ..|..|:|.::|||..|....::..||.|:.:....|.|.:|..:
Yeast 1467 SLNAFSGATGGIAYCLTSDYDDFVGKINKDTVELESLCDPVEIAFVKNLIQEHWNYTQSDLAARI 1531
Fly 1550 LDNWAEAQGKFVKVFPYEYQKA-LKDMAE---------------------------------QQA 1580
|.|:......||||.|.:|:|. ||:.|| |:|
Yeast 1532 LGNFNHYLKDFVKVIPTDYKKVLLKEKAEAAKAKAKATSEYLKKFRSNQEVDDEVNTLLIANQKA 1596
Fly 1581 VEQPLKSAIENGNGK--HEPHIKDIEEAIQDVVLEQKRADRVLDKTRGFVKYKRESAPYRDAGER 1643
.||..|.:|...|.. .||.:.|:|:|:.|....:|.::|: :|||||:.:||....:||...|
Yeast 1597 KEQEKKKSITISNKATLKEPKVVDLEDAVPDSKQLEKNSERI-EKTRGFMIHKRRHETHRDPRTR 1660
Fly 1644 QKDWDEVYNFPHVRKNLKVQAARCMECGVPFCQSNSTGCPLGNIIPKWNDLVFHGEWQEALRQLL 1708
..||.|..| |..:|:.|.|.||||:||.|||.|: |||||.|||||:|:|:|..:|:.||.:||
Yeast 1661 VNDWKEFTN-PITKKDAKYQTARCMDCGTPFCLSD-TGCPLSNIIPKFNELLFKNQWKLALDKLL 1723
Fly 1709 QTNNFPEFTGRVCPAPCEGSCVLGISEPAVTIKNIECAIIDHAFEQGWIKPEIPEVRTGKRVAIV 1773
:||||||||||||||||||:|.|||.|..|.||::|..|||:||::|||||..|..|||..|.::
Yeast 1724 ETNNFPEFTGRVCPAPCEGACTLGIIEDPVGIKSVERIIIDNAFKEGWIKPCPPSTRTGFTVGVI 1788
Fly 1774 GSGPSGLAASQQLNRAGHFVTVFERNDRVGGLLQYGIPTMKLSKEVVKRRVDLMADEGIEFRTNV 1838
||||:|||.:..||||||.|||:||:||.||||.||||.|||.|.:|:||:||::.|||:|.||.
Yeast 1789 GSGPAGLACADMLNRAGHTVTVYERSDRCGGLLMYGIPNMKLDKAIVQRRIDLLSAEGIDFVTNT 1853
Fly 1839 HVGKDLKAEQLLQEYDAVLLTTGSTWPRDLPLANRDLKGIHFAMEFLEAQQKKQLGGKNDII--S 1901
.:||.:..::|..:::||:...|||.|||||:..|:||.|.|||:.||:..|..|....:|| .
Yeast 1854 EIGKTISMDELKNKHNAVVYAIGSTIPRDLPIKGRELKNIDFAMQLLESNTKALLNKDLEIIREK 1918
Fly 1902 AAGKNVIIIGGGDTGCDCIATSLRQGAKSITTFEILPEPPQKRAQDNPWPQWPKVFRVDYGHEEV 1966
..||.||::||||||.||:.||:|.||.|:..||:|||||.:||:||||||||:|.||||||.||
Yeast 1919 IQGKKVIVVGGGDTGNDCLGTSVRHGAASVLNFELLPEPPVERAKDNPWPQWPRVMRVDYGHAEV 1983
Fly 1967 KLKWGKDPRQYCTTTKEFVG-ENGAIKGVNTVEVEWTKTETGQWRMQEVAGSEKYFPADLILLAM 2030
|..:|:|||:||..:|||:| :.|.:..:.||.|||.|:::|.|:|.|:..||:.|.||:|||:|
Yeast 1984 KEHYGRDPREYCILSKEFIGNDEGEVTAIRTVRVEWKKSQSGVWQMVEIPNSEEIFEADIILLSM 2048
Fly 2031 GFLGPEKTVPSELGLELDPRGNIKA-SNGQYGTSNSKVFAAGDCRRGQSLVVWAITEGRQAARQV 2094
||:|||....::..::...||.|.. .:..|.....|.||.|||||||||:||||.|||:.|..|
Yeast 2049 GFVGPELINGNDNEVKKTRRGTIATLDDSSYSIDGGKTFACGDCRRGQSLIVWAIQEGRKCAASV 2113
Fly 2095 DSYLTGRPSGLPGPGGVI 2112
|.:|....:.||..||::
Yeast 2114 DKFLMDGTTYLPSNGGIV 2131
| 
