DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9674 and F20D6.11

DIOPT Version :9

Sequence 1:	NP_001246804.1	Gene:	CG9674 / 39878	FlyBaseID:	FBgn0036663	Length:	2115	Species:	Drosophila melanogaster
Sequence 2:	NP_505112.1	Gene:	F20D6.11 / 179196	WormBaseID:	WBGene00017640	Length:	549	Species:	Caenorhabditis elegans

Alignment Length:	460	Identity:	102/460 - (22%)
Similarity:	176/460 - (38%)	Gaps:	148/460 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1718 GRV-CPAPCEGSC--------------------VLGISEPAVTIKNIECAI-----IDHAFEQGW 1756
            ||: |  |..|:|                    |:.:::..:.||..|..:     |.|
Worm    78 GRIRC--PLHGACFNVRSGDIEDYPGFDSLHSYVVTVNDGNLIIKTTEKKLGSDRRIRH------ 134

  Fly  1757 IKPEIPEVR--TGKRVAIVGSGPSGLAASQQLNRAGHFVTVFERNDRVGGLLQYGIPTMKLSKE- 1818
                :|:::  ..:.|.|:|.|.:              ...|..:.|:.||:   .|.:.:|:|
Worm   135 ----LPKMKQCNDRPVVIIGGGVA--------------TATFIEHSRLNGLI---TPILVISEES 178

  Fly  1819 -------------------VVKRRVDLMADE-GIEF--RTNV----HVGKDL---KAEQLLQEYD 1854
                               :..|:.|...:| .::|  :|:|    |..:::   ..|.::  |.
Worm   179 LPPYDRVLLSKKPAATGEDIRLRKDDAFYEERNVKFLLKTSVIAVNHKSREVSLSNGETVV--YS 241

  Fly  1855 AVLLTTGSTWPRDLPLANRDLKGIHFAMEFLEAQQKKQLGGKNDIIS--AAGKNVIIIGGGDTGC 1917
            .:::.||.. .|.|.:...|||.|.:..:..||          :|||  ..||:|:.:|....|.
Worm   242 KLIIATGGN-VRKLQVPGSDLKNICYLRKVEEA----------NIISNLHPGKHVVCVGSSFIGM 295

  Fly  1918 DCIATSLRQGAKSITTFEILPEP-PQKRAQDNPWPQWPKVFRVDYGHEEVKLKWGKDPRQYCTTT 1981
            : :|::|.:.|.|:|.....||| |              ||..|.| :.::||:.:...::
Worm   296 E-VASALAEKAASVTVISNTPEPLP--------------VFGSDIG-KGIRLKFEEKGVKF---- 340

  Fly  1982 KEFVGENGAIKGVNTVEVEWTKTETGQWRMQEVAGSEKYFPADLILLAMGFLGPEKTVPSELGLE 2046
             |......|::|.:..||.....|.|           |....||::..:|.....|.:... |::
Worm   341 -ELAANVVALRGNDQGEVSKVILENG-----------KELDVDLLVCGIGVTPATKFLEGS-GIK 392

  Fly  2047 LDPRGNIKASNGQYGTSNSKVFAAGDCRRGQSLVVWAIT-------EGRQAARQVDSY-LTGRPS 2103
            ||.||.|:... ::.|:.|.:||.||.... .|.:|.|.       :..||..|...| :.|:|.
Worm   393 LDNRGFIEVDE-KFRTNISYIFAMGDVVTA-PLPLWDIDSINIQHFQTAQAHGQHLGYTIVGKPQ 455

  Fly  2104 GLPGP 2108
              |||
Worm   456 --PGP 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9674	NP_001246804.1	gltB	75..1565	CDD:236968
		GATase_2	88..504	CDD:278726
		Glu_syn_central	543..828	CDD:282720
		GltS_FMN	918..1271	CDD:239202
		gltB_C	1316..1565	CDD:238482
		gltD	1623..2106	CDD:237213	99/456 (22%)
		Fer4_8	1645..1756	CDD:302761	12/63 (19%)
		NAD_binding_8	1772..>1804	CDD:290186	5/31 (16%)
F20D6.11	NP_505112.1	Rieske_AIFL_N	29..118	CDD:239560	7/41 (17%)
F20D6.11	NP_505112.1	Pyr_redox_2	147..443	CDD:369639	81/360 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910