DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eIF3e and EIF3E

DIOPT Version :9

Sequence 1:	NP_477385.1	Gene:	eIF3e / 39877	FlyBaseID:	FBgn0025582	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_567047.1	Gene:	EIF3E / 824896	AraportID:	AT3G57290	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	438	Identity:	195/438 - (44%)
Similarity:	292/438 - (66%)	Gaps:	24/438 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NFDLTRINCQFLDRHLTFPLLEFLCGKEIYNQQELLEYILETVNKTNMIDYTMDTRKRLNLSQEM 67
            |:|||.:....|||||.||:.|||..:::|..:::|:..::.:|:|||:||.||..|.|..:::.
plant     7 NYDLTPLIAPNLDRHLVFPIFEFLQERQLYPDEQILKSKIQLLNQTNMVDYAMDIHKSLYHTEDA 71

  Fly    68 PEELVQRKAEVLATLKQLQNEVAPIMKATDILKNGESMK----DSKTFVNALQKDYNFKVEHLES 128
            |:|:|:|:.||:|.||.|:...||::   ..|.|..:::    |.:..:..|::.|....:.:|:
plant    72 PQEMVERRTEVVARLKSLEEAAAPLV---SFLLNPNAVQELRADKQYNLQMLKERYQIGPDQIEA 133

  Fly   129 AYKLAKYLYECGNYQESTSYLYFCLIVMSPNDKNYLNVLWGKLAAEILTLNWNTALEDLTRLRDY 193
            .|:.||:.:|||||..:..|||....:.| |.:..|:.||||||:|||..||:.|||:|.||::.
plant   134 LYQYAKFQFECGNYSGAADYLYQYRTLCS-NLERSLSALWGKLASEILMQNWDIALEELNRLKEI 197

  Fly   194 IDNANFST-IQALQQRTWLIHWSVLVFFNHPKGRDLIIEMFLYKPLYLNAIQTMCPHIMRYLATA 257
            ||:.:||: :..:|.|.||:||.:.:||||..||..||::| .:..|||||||..||::||||||
plant   198 IDSKSFSSPLNQVQNRIWLMHWGLYIFFNHDNGRTQIIDLF-NQDKYLNAIQTSAPHLLRYLATA 261

  Fly   258 VVINRTRRNALKDLIKVIQQESYTYRDPITEFLECLYVNFDFEGARLKLHECQTVILNDFFI--- 319
            .::|:.||..||:.|||||||.|:|:|||.|||.|::||:||:||:.|:.||:.||:||.|:
plant   262 FIVNKRRRPQLKEFIKVIQQEHYSYKDPIIEFLACVFVNYDFDGAQKKMKECEEVIVNDPFLGKR 326

  Fly   320 --------VACLNEFVEDARLMIFETFCRIHQCITISMLADKLNMKPNEAECWIVNLIRNARLNA 376
                    |...:||:|:|||.:|||:|:|||.|.:.:||:|||:...|||.|||||||.::|:|
plant   327 VEDGNFSTVPLRDEFLENARLFVFETYCKIHQRIDMGVLAEKLNLNYEEAERWIVNLIRTSKLDA 391

  Fly   377 KIDSKLGHVVM-GTQPLSPYQQLVEKIDSLSMRSEHLAG-LIERKSKQ 422
            ||||:.|.|:| .||| :.::||:.....||.|:..|.. |:|....|
plant   392 KIDSESGTVIMEPTQP-NVHEQLINHTKGLSGRTYKLVNQLLEHTQAQ 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3e	NP_477385.1	eIF3E	3..418	CDD:411062	193/432 (45%)
EIF3E	NP_567047.1	eIF3E	7..433	CDD:411062	193/431 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	156	1.000	Domainoid score	I1317
eggNOG	1	0.900	-	-		E1_KOG2758
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1205
Inparanoid	1	1.050	368	1.000	Inparanoid score	I571
OMA	1	1.010	-	-		QHG55232
OrthoDB	1	1.010	-	-		D1151808at2759
OrthoFinder	1	1.000	-	-		FOG0003441
OrthoInspector	1	1.000	-	-		oto3078
orthoMCL	1	0.900	-	-		OOG6_102060
Panther	1	1.100	-	-	LDO	PTHR10317
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2338
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840