Protein Alignment CG13025 and rfwd3

DIOPT Version :9

• Sequence 1: NP_001261971.1
• Gene: CG13025 / 39874
• FlyBaseID: FBgn0036660
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_002667008.1
• Gene: rfwd3 / 100329327
• ZFINID: ZDB-GENE-120529-1
• Length: 632
• Species: Danio rerio
• Alignment Length: 603
• Identity: 169/603 - (28%)
• Similarity: 262/603 - (43%)
• Gaps: 70/603 - (11%)

  Fly    31 NPVEGLQPAVEIDEQRD-QPGENAEPEQPRVPPLILVDPPHLPSPPRNSRRNQGEEQEVISLETP 94
            ||.:...|.   |.:.| :|..:...:|.||........|..||.|      ...|...:.|:|.
Zfish    67 NPPDTHNPP---DTRTDPEPASSDSADQSRVQSTAETSSPAGPSVP------AAAEAPAVELKTE 122

  Fly    95 SPPKKRKRLSAAADKSLKKSPEGKPIVVDDED-DGMTCPICLDSWEMSGEHRLVSLRCGHLFGES 158
            .........||||      ||.|   ..|:.| :|.:|.||.:.|..:|||||.:||||||||..
Zfish   123 VEASSDSSGSAAA------SPAG---AADEADTEGESCSICFEPWTTAGEHRLAALRCGHLFGYV 178

  Fly   159 CIRRWLNESHRQSSVKVCPQCKTKATFRDIRHLYAKRIQMLDTD----IREQLEAER--RRTHTL 217
            ||.|||.....:     ||||...|....|..|||:|::.||..    ::.:||.|:  ||...|
Zfish   179 CISRWLTGGGNK-----CPQCNKPAKKTQIIFLYARRLKALDNTEEVRLKSRLELEQGSRRMEQL 238

  Fly   218 TTELATAKLANTLTTEKLILLQKDYERLKE-LVRAGGGRGAFGGDASGQKSIQQLATYRLYMEKN 281
              |:|..:....|..::...|:|:.|.|:. ..:|..|    ...|:...|.|:..:......|.
Zfish   239 --EVAQCRQQLQLMVDENTRLRKEVEELRRWKAQASAG----SSQAASLSSSQRQDSGHYVFSKA 297

  Fly   282 FEITRDPGCRVLLYSAKHSMLVASQKSAQ-NLFPGYGVRFIDPPTFKPLQFLHTSALLIRDIAFS 345
            ..:::..|.|||.:......|:|||.|.| .|.||:||:.|...|.|..|::|..:..||.:|||
Zfish   298 VLVSQTGGSRVLAHCEPLGCLLASQPSPQATLMPGFGVKKISTATLKASQYVHIHSKQIRGLAFS 362

  Fly   346 DSQH-LLTVASRELKIKIFDIRTRLCSSMFTAHDKMLWSCAL--DRNEREHFLYGGDLRGGVYIY 407
            ..|. ||..|:.:..||:..:.|......:.. .:.:|||..  |.|   :::|.|...|.|.:|
Zfish   363 QQQDGLLLSAALDNTIKLTSLMTNTVVQAYNT-GRPVWSCCWCHDNN---NYIYAGLSNGSVLVY 423

  Fly   408 DLRFPENILCEFQAEVNLSPVIHIAPV---QPNKIFTSGGFLVCQLTALTFYEYAAASDTAVPTR 469
            |.|.....:.|.:...:..||:.::.:   ..:..|..||.:...|....|:| ....:|..|..
Zfish   424 DTRDTSTHVQELRPLRSSCPVVSLSYIPHSSTSSSFPCGGVIAGTLEGGCFWE-RHNDNTHTPHI 487

  Fly   470 LNVE-GPFLSMQYDAVQDTVLISARSNPNFPQSRFILGRMDKIDGTPVLKVKATIYGSKATPVMT 533
            |.:| |....:|.:|.....|::.|.....|..|.:|..:.:   ||.:.:::::  ...:||.|
Zfish   488 LPLESGNCTHIQAEAESRHCLVTYRPGRLNPSLRCVLMELSR---TPQVDLQSSV--CSCSPVQT 547

  Fly   534 ----RPTQLAVED----------NTLVVGYLQDSKQLMMHDVRREERVQTMPVNEVIYDICPVAT 584
                ...:|..::          ..||....:.:...|:.|......:|.||.:..:.||||...
Zfish   548 FSAGSSCKLLTKNCVFRSPAGGGAALVCAGDEATNSTMVWDAGTGALLQKMPADLPVLDICPFEA 612

  Fly   585 QAGSYLAALTDNKCRVYK 602
            ...|:||:||:...:|||
Zfish   613 NQSSFLASLTEKMIKVYK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13025	NP_001261971.1	zf-RING_2	130..180	CDD:290367	25/49 (51%)
		WD40	<293..445	CDD:295369	46/158 (29%)
		WD40	<318..>415	CDD:225201	30/99 (30%)
		WD40 repeat	339..375	CDD:293791	12/36 (33%)
rfwd3	XP_002667008.1	RING	151..197	CDD:238093	26/50 (52%)
		DUF972	227..>266	CDD:283750	12/40 (30%)
		WD40	<335..>484	CDD:225201	40/153 (26%)
		WD40	337..>458	CDD:295369	32/124 (26%)
		WD40 repeat	356..393	CDD:293791	12/36 (33%)
		WD40 repeat	399..440	CDD:293791	13/43 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579730
Domainoid	1	1.000	106	1.000	Domainoid score	I6554
eggNOG	1	0.900	-	-		E1_KOG1645
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41230
Inparanoid	1	1.050	172	1.000	Inparanoid score	I4083
OMA	1	1.010	-	-		QHG49616
OrthoDB	1	1.010	-	-		D273025at33208
OrthoFinder	1	1.000	-	-		FOG0007495
OrthoInspector	1	1.000	-	-		oto39888
orthoMCL	1	0.900	-	-		OOG6_104706
Panther	1	1.100	-	-	LDO	PTHR16047
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6377
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810