Protein Alignment Nrt and NLGN4X

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_005274621.1
• Gene: NLGN4X / 57502
• HGNCID: 14287
• Length: 836
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 99/346 - (28%)
• Similarity: 140/346 - (40%)
• Gaps: 97/346 - (28%)

  Fly   368 GPVEGVKEDGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTV 432
            ||||        .:.|:|||.||....|::|.|....    |.....|...:.||.|.|...:.:
Human    68 GPVE--------QYLGVPYASPPTGERRFQPPEPPSS----WTGIRNTTQFAAVCPQHLDERSLL 120

  Fly   433 GD---------------------EDCLYLDVVTP-------------------------HVRYNN 451
            .|                     ||||||::..|                         |.: |:
Human   121 HDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDGANTKKNADDITSNDRGEDEDIHDQ-NS 184

  Fly   452 PLPVVVLIGAESLAGPSPGILRPS--ARYSRSHDVIFVRPNFRLGVFGFLAL-DALTKEAHPPTS 513
            ..||:|.|...|....:..::..|  |.|.   :||.:..|:|||:.|||:. |...|
Human   185 KKPVMVYIHGGSYMEGTGNMIDGSILASYG---NVIVITINYRLGILGFLSTGDQAAK------- 239

  Fly   514 GNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAI 578
            |||.|.|.|..|.||:.|:..|||||:.||:.|..|||:.|:||..|...:||:.:|...||:|:
Human   240 GNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTAL 304

  Fly   579 LPGKPLSESGKQNEQLMATLEC-----AD-IQCLREASSERL--WAATPDTWLHFPVDLPQPQEA 635
            .......:..|....|...:.|     .| ::|||..:.:.|  ...||.|: |.
Human   305 SSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATY-HI---------- 358

  Fly   636 NASGSRHEWLVLDGDVVFEHP 656
             |.|.     |:||||:.:.|
Human   359 -AFGP-----VIDGDVIPDDP 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	99/346 (29%)
NLGN4X	XP_005274621.1	COesterase	42..610	CDD:278561	99/346 (29%)
		Aes	<179..>286	CDD:223730	45/117 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810