Protein Alignment Nrt and alpha-Est1

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 135/550 - (24%)
• Similarity: 214/550 - (38%)
• Gaps: 132/550 - (24%)

  Fly   335 VLLLG--VIGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVK------EDGAFAFRGIPYAKPPV 391
            :|.:|  :||:.:....|.:...:     :..|..|.|.|.:      |:..|||.|||:|:|||
  Fly    10 LLKMGTKLIGHKIVQYRLGTKQTK-----VVCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPV 69

  Fly   392 DRLRWK------PAELIDDINMCWNDTLQTH-NSSVVCTQRLGNGTTVGDEDCLYLDVVTPHVRY 449
            ..||::      |...:.|........:|.| ..|:|          .|.||||||:|.:..:|.
  Fly    70 GELRFRAPQPPHPWLGVRDCTYPRAKPMQKHFVLSIV----------EGSEDCLYLNVYSKRLRS 124

  Fly   450 NNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSG 514
            :.||||:|.|..........|....|..|....||:.|..|:|:|..|||:|  ..::...|  |
  Fly   125 DKPLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVVVTFNYRVGALGFLSL--ADRDLDVP--G 185

  Fly   515 NYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAIL 579
            |..|.|.:..|.||..||..|.||||::|::|..|||..|..|:.:::.:||:.:|...|||...
  Fly   186 NAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVHALMTTEQTRGLFHKAIMQSGSMFC 250

  Fly   580 --PGKP-----------LSESGKQNE-------QLMATLECADIQCLREASSER----LWAATPD 620
              ..:|           |..||.:||       |.....|.|.......:..||    |:..||.
  Fly   251 EWANEPSGRWAYRLACQLGYSGSENEKEVFRYLQKAPASEMAAQGITLVSQEERRQYVLFPFTPV 315

  Fly   621 TWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHEA----- 680
            ...:...|...|:      ...|.|           .:.|    .||.| |::|..:.|.
  Fly   316 VEPYITRDCVLPR------CHREML-----------PEAW----GNDLP-LILGGNSFEGLFSYQ 358

  Fly   681 ---HTEK----------LRELHANWTREEVRAYLENSQIGALGLTDEVIEKYNASSYASLVSI-- 730
               |.|:          .||:....|:..::..|...::.  ...|....:...:....::|:
  Fly   359 STLHDEEHMLSAFEVLIPREIREKSTQSHLKDLLRQFKVD--NFDDATRGRMEFNECLHILSVKH 421

  Fly   731 ----ISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDADV-------QAILGRYEPHTVE 784
                |.  |:|...|::|   |:.|.|          |...|.|.       |.:.|::    |.
  Fly   422 FWHGIH--RTVLARLSHA---PATPTY----------LYRFDVDSPHFNHFRQVMCGKH----VR 467

  Fly   785 QRRFVSAMQQLFYYYVSHGTVQSFVQNRRV 814
            .......:..|||:.:::...:|.::.:.:
  Fly   468 GVSHADDLSYLFYHILANKVDKSSMEYQTI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	130/520 (25%)
alpha-Est1	NP_524269.3	COesterase	31..555	CDD:395084	130/528 (25%)