Protein Alignment Nrt and Est-P

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 130/582 - (22%)
• Similarity: 228/582 - (39%)
• Gaps: 126/582 - (21%)

  Fly   328 VFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKEDGA-FAFRGIPYAKPPV 391
            :|..||.:.||    ::...|:...|      .|:.:|. |.:.| |::|. :::..||.|:.|.
  Fly     3 IFKRLLCLTLL----WIAALESEADP------LIVEITN-GKIRG-KDNGLYYSYESIPNAEHPT 55

  Fly   392 DRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ----RLGNGTTVGDEDCLYLDVVTPHVRYNNP 452
            ..||:   |.....:..|.|......|.|.|.|    ...|...:||||||.:.:..|.....:.
  Fly    56 GALRF---EAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSS 117

  Fly   453 LPVVVLI-------GAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHP 510
            .|||||:       |:.|:.| ...|:|...       ::.|:.:|.||..||    |.|.:.|.
  Fly   118 FPVVVLLHGGAFMFGSGSIYG-HDSIMREGT-------LLVVKISFGLGPLGF----ASTGDRHL 170

  Fly   511 PTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSG 575
            |  |||.|.|....|.|||.||.||||.|.::.|:||.||.....|.:..:..|.|...|.:.||
  Fly   171 P--GNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSG 233

  Fly   576 SAILPGKPLSESGKQNE-QLMATLEC------ADIQ-CLREASSERLWAATPD----TWLHF--- 625
            :|:.|. .:.:.|::.. :|...:.|      |::: ||:...:..:.:|...    :::.|
  Fly   234 NALDPW-VIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAF 297

  Fly   626 -----PVDLP------QPQEANASG--SRHEWLVLDGDVVFEHPSDTWKREQA--NDKPVLVMGA 675
                 |.|.|      .|:....||  ::..|.|            |:..|..  |...:|....
  Fly   298 GPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAV------------TYTTEDGGYNAAQLLERNK 350

  Fly   676 TAHEAHTEKLRELHANWT-----REEVRAYLENSQIGALGLTDEVI--EKYNASSYASLVSIISD 733
            ...|:..:.|.:...:|.     ..:.:..:::....:..|..:.:  .:::..||.::..:.:|
  Fly   351 LTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTD 415

  Fly   734 I---RSVCPLLTNARQQPSVPFYVVTQGEGPD-------------QLATVDADVQAIL------- 775
            :   .||...:...|:....|.|........|             ...||..|...::
  Fly   416 VLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYR 480

  Fly   776 -GRYEPHTVEQRRFVSAMQQLFYYYVSHGTV-------QSFVQNR--RVINVGQDAQPEEDY 827
             |......|..::|:..::.  :.....||:       |:.|.::  :|:.:.::|...|:|
  Fly   481 TGIRPDEEVISKKFIGMLED--FALNDKGTLTFGECNFQNNVNSKEYQVLRISRNACKNEEY 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	122/548 (22%)
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	121/544 (22%)