DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrt and SPCC417.12

DIOPT Version :9

Sequence 1:	NP_001189121.1	Gene:	Nrt / 39873	FlyBaseID:	FBgn0004108	Length:	846	Species:	Drosophila melanogaster
Sequence 2:	NP_588289.2	Gene:	SPCC417.12 / 2539430	PomBaseID:	SPCC417.12	Length:	539	Species:	Schizosaccharomyces pombe

Alignment Length:	493	Identity:	125/493 - (25%)
Similarity:	194/493 - (39%)	Gaps:	136/493 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 VTGCGPVEG---VKEDG---AFAFRGIPYAKPPVDRLRW-KPAELID--DINMCWNDTLQTHNSS 419
            :.|.|.:.|   :.|:|   ...|.||.||||||.:||| :|..|.|  |.:..:|      ...
pombe    17 IPGMGVLHGLTVLDENGKEKCHRFTGIRYAKPPVGKLRWRRPVTLEDGYDYSGDYN------QFK 75

  Fly   420 VVCTQ--------RLGNGTTVGDEDCLYLDVVTP---------------H---VRYNNPLPVVVL 458
            .:|.|        ::.|.....|||||:|::..|               |   ::..|||.....
pombe    76 TICPQPFYNNRKNQVRNPDFKYDEDCLFLNIWVPAGEKPAEGWPVLYFIHGGWLQVGNPLHYRQC 140

  Fly   459 IGAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIA 523
            ...:..|..||      |::      |.|.|..||.:|||||...|.:|  .|.|.|:...|...
pombe   141 DPQDLQADGSP------AKF------ILVSPGHRLNLFGFLAGKELLEE--DPKSSNFGFWDQRL 191

  Fly   524 VLNWIKLNIVHFGGDPQSVTLLGHRAG--ATLVTLLVNS--QKVKGLYTRA-WASSGSAILPGKP 583
            .|.|...:|..|||:.:::.:.|..||  :.|..|:..:  .:...:..|| ..|:|.::.| |.
pombe   192 GLEWTYKHIESFGGNKENIAVGGISAGSYSALFQLIYETYHPEANQIIKRALLLSNGLSVQP-KS 255

  Fly   584 LSESGKQNEQLM----ATLECADIQCLREASSERLWAATPDTWLHFPVDLP-QPQEANASGSR-H 642
            :.||..|..:|.    ..||.:..:.|     |:|.|            :| |....|....| |
pombe   256 VEESQIQFNELAQKFGIPLELSSAEKL-----EKLRA------------IPFQDLADNILNLRLH 303

  Fly   643 EW-LVLDGDVVFEHPSDTWK-----------REQANDKPVLVMGATAHE----AHT------EKL 685
            .: .|.|||  |.:| :|:|           |:...:   |::|...:|    |:|      |.|
pombe   304 TFRAVTDGD--FVNP-NTFKDIYDGTFGKRIRDSGRE---LIIGEVNNEHSIYANTNPPKSKEDL 362

  Fly   686 RELHANWTREEVRAYLENSQIGALGLTDEVIEKYNASSYASLVSIISDIR--SVCPLLTNARQQP 748
            .....|:..|:|...|.........:.||  ::|.|:..|...||:||::  :...:|.|...:.
pombe   363 FNQVNNYYPEKVTKALLELYPKVPDMEDE--KEYLAAIKALFGSIVSDMQVYASTRVLINGLVKG 425

  Fly   749 SVP------FYVVTQGEGPDQLATVDADVQAILGRYEP 780
            .||      :.:..:|:              ...:|||
pombe   426 GVPLEKIYRYRIAFRGK--------------FFDKYEP 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	125/493 (25%)
SPCC417.12	NP_588289.2	PnbA	20..534	CDD:225181	124/490 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900