DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrt and Cel

DIOPT Version :9

Sequence 1:	NP_001189121.1	Gene:	Nrt / 39873	FlyBaseID:	FBgn0004108	Length:	846	Species:	Drosophila melanogaster
Sequence 2:	NP_058693.2	Gene:	Cel / 24254	RGDID:	2331	Length:	612	Species:	Rattus norvegicus

Alignment Length:	377	Identity:	105/377 - (27%)
Similarity:	153/377 - (40%)	Gaps:	113/377 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 LFVLLLGV-----------IGYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKE-------DGAF 379
            |.||.||:           :|.|.|          ||         |.||||.:       |...
  Rat     4 LEVLFLGLTCCLAAACAAKLGAVYT----------EG---------GFVEGVNKKLSLLGGDSVD 49

  Fly   380 AFRGIPYA-KPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ-RLGNGTTVGDEDCLYLDV 442
            .|:|||:| ...::..:..|.         |..||:..:....|.| .:....|.|.||||||::
  Rat    50 IFKGIPFATAKTLENPQRHPG---------WQGTLKATDFKKRCLQATITQDDTYGQEDCLYLNI 105

  Fly   443 VTPHVR--YNNPLPVVVLI-GAESLAGPSPGILRPSARYSRSH-----------DVIFVRPNFRL 493
            ..|..|  .::.|||:|.| |...|.|...|     |.:.:::           :||.|..|:|:
  Rat   106 WVPQGRKQVSHDLPVMVWIYGGAFLMGSGQG-----ANFLKNYLYDGEEIATRGNVIVVTFNYRV 165

  Fly   494 GVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLV 558
            |..|||:    |.:|:.|  ||:.|.|....:.|:|.||..|||||.::|:.|..|||..|:|..
  Rat   166 GPLGFLS----TGDANLP--GNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQT 224

  Fly   559 NSQKVKGLYTRAWASSGSAILP------------------GKPLSESGKQNEQLMATLECADIQC 605
            .|...|||..||.:.||.|:.|                  |.|..::.|    :...|:..|.:.
  Rat   225 LSPYNKGLIRRAISQSGVALSPWAIQENPLFWAKTIAKKVGCPTEDTAK----MAGCLKITDPRA 285

  Fly   606 LREASSERLWAATPD-TWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHP 656
            |..|  .||...:.: ..:|:...:|               |:|||.:.:.|
  Rat   286 LTLA--YRLPLKSQEYPIVHYLAFIP---------------VVDGDFIPDDP 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	95/337 (28%)
Cel	NP_058693.2	COesterase	26..542	CDD:278561	99/355 (28%)
		Aes	<118..>247	CDD:223730	51/139 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	553..612
		4 X 11 AA tandem repeats, O-glycosylated region	556..599
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900