Protein Alignment Nrt and NLGN1

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_001352852.1
• Gene: NLGN1 / 22871
• HGNCID: 14291
• Length: 843
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 114/411 - (27%)
• Similarity: 162/411 - (39%)
• Gaps: 114/411 - (27%)

  Fly   320 CSVDDALIVFGILLFVLLLGVI---GYVLTHETLTSPPLREGRYIMAVTGCGPVEGVKED----- 376
            |.|...|   |..|.:.:||.:   |:||:.:.....||       ..|..|.:.|:|::
Human    19 CLVHRGL---GAPLTLCMLGCLLQAGHVLSQKLDDVDPL-------VATNFGKIRGIKKELNNEI 73

  Fly   377 --GAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNG---------- 429
              ....|.|:|||.||....|::|.|....    |:|.......:.||.|.:.:|
Human    74 LGPVIQFLGVPYAAPPTGERRFQPPEPPSP----WSDIRNATQFAPVCPQNIIDGRLPEVMLPVW 134

  Fly   430 ---------TTVGD--EDCLYLDVVTP-----------------------HVR-YNNPLPVVVLI 459
                     :.|.|  ||||||::..|                       .:| ...|.||:|.|
Human   135 FTNNLDVVSSYVQDQSEDCLYLNIYVPTEDGPLTKKQTDDLGDNDGAEDEDIRDSGGPKPVMVYI 199

  Fly   460 -GAESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLAL-DALTKEAHPPTSGNYALTDII 522
             |...:.|  .|.|...:..:...:||.:..|:||||.|||:. |...|       |||.|.|:|
Human   200 HGGSYMEG--TGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAK-------GNYGLLDLI 255

  Fly   523 AVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVN---------SQKVKGLYTRAWASSGSAI 578
            ..|.|...||..|||||..:|:.|..||.:.|.||..         |...|||:.||.|.||:|:
Human   256 QALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 320

  Fly   579 LPGKPLSESGKQNEQLMATLEC--AD----IQCLREASSERLWAATPDTWLHFPVDLP-QPQEAN 636
            .......:..|....|...:.|  :|    ::||::...:.|            ||.. ||...:
Human   321 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKEL------------VDQDIQPARYH 373

  Fly   637 -ASGSRHEWLVLDGDVVFEHP 656
             |.|.     |:||||:.:.|
Human   374 IAFGP-----VIDGDVIPDDP 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	102/366 (28%)
NLGN1	NP_001352852.1	COesterase	53..626	CDD:365897	104/374 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810