Protein Alignment Nrt and Ces2e

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_001093947.1
• Gene: Ces2e / 192257
• RGDID: 621563
• Length: 557
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 150/574 - (26%)
• Similarity: 237/574 - (41%)
• Gaps: 121/574 - (21%)

  Fly   327 IVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEG----VKE--DGAFAFRGIP 385
            :|:|:||  |...|.|..      ::.|:|.       |..|.|.|    ||:  .|...|.|||
  Rat    13 VVWGLLL--LFCQVQGQD------SASPIRN-------THTGQVRGSFVHVKDTKSGVHTFLGIP 62

  Fly   386 YAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ------------RLGNGTTVGDEDCL 438
            :||||:..||:.|.|..:.    |:......:...:|.|            ::........||||
  Rat    63 FAKPPIGPLRFAPPEPPEP----WSGVRDGTSHPAMCLQNIDGLNLENLKIKMSRSPVSMSEDCL 123

  Fly   439 YLDVVTP-HVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRS-----HDVIFVRPNFRLGVFG 497
            ||.:.|| |...::.|||:|.|....|..   |:   ::.|..|     .||:.|...:|||:.|
  Rat   124 YLSIYTPAHTHKDSNLPVMVWIHGGGLCW---GM---ASTYDGSMLAAIEDVVVVTIQYRLGILG 182

  Fly   498 FLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQK 562
            |.:    |.:.|  ..||:...|.:|.|.|::.|||||||:|..||:.|..||...|:..|.|..
  Rat   183 FFS----TGDEH--ARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPM 241

  Fly   563 VKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLE-C------ADIQCLREASSERLWAATPD 620
            .:||:..|...||.|:||.. :|.:.:....::|.|. |      |.:.||||.|.|.:.|....
  Rat   242 SQGLFHGAIMESGVALLPNL-ISNTSEVIYTMVANLSGCEPVDSEALMSCLREKSEEEMLAINNI 305

  Fly   621 TWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHE------ 679
            .             ...||      |:||..:..||.:.......:..|.:: |..:.|
  Rat   306 V-------------RTISG------VVDGKFLPRHPLELLASVDFHPVPSII-GINSDEYGWIIP 350

  Fly   680 -AHTEK-LRELHANWTREEVRAYLENSQIGAL---GLTDEVIEKYNASSYASLV------SIISD 733
             .|.:. ::|::    ||.:||.|:|:.:..:   ..:|.::|:|...:..|..      .::.|
  Rat   351 MLHPDSTMKEIN----RETMRAVLKNTAVQMMLPPECSDLLMEEYMGDTEDSKTLQIQFNEMMGD 411

  Fly   734 IRSVCPLLTNAR-QQPSVPFYVVTQGEGPDQLATV-DADVQAILGRYEPHTVEQRRFVSAMQQLF 796
            ...|.|.|..|. |:...|.|........:.|..: ...|:|..|...|:.:         ..||
  Rat   412 FIFVIPALQVAHFQRSHAPVYFYEFQHQSNFLKDIRPPHVKADHGDELPYVI---------GYLF 467

  Fly   797 YYYVSHGTVQSFVQNRRVI----NVGQDAQPEEDYLPCNYWISKDIVPRYARVD 846
            :......|.:..:.:|::|    |..:...|..:.||  ||.:.|...:|.::|
  Rat   468 WDMKFVFTEEEKLLSRKMIKYWANFARHGNPNSEGLP--YWPALDHDEQYLQLD 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	136/523 (26%)
Ces2e	NP_001093947.1	COesterase	30..536	CDD:395084	143/549 (26%)