Protein Alignment Nrt and cest-31

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 131/524 - (25%)
• Similarity: 186/524 - (35%)
• Gaps: 158/524 - (30%)

  Fly   367 CGPVEG----VKEDGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ--- 424
            ||||:|    ...:....:.|||||:||:..||:|.....|    .|.:|..       ||:
 Worm    21 CGPVQGNLYRHGNEEVHGYLGIPYAQPPIGILRFKKPVSAD----VWTETRD-------CTKYGP 74

  Fly   425 ------------RLGNGTTVGDE-DCLYLDVVTP--HVRYNNPLPVVVLI---GAE--------- 462
                        :|.| |.:.|| :||.|:|..|  .::.:...||::.|   |.|
 Worm    75 RCPPSGMLYENLQLPN-TDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFIHGGGFELSASKDYCD 138

  Fly   463 -SLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLN 526
             ||:|..|           ..|||.|..|:|:|..|||.      .......||:.|.|:...|.
 Worm   139 YSLSGTLP-----------LKDVIVVTVNYRVGALGFLT------TGDDSCRGNFGLWDLTLALK 186

  Fly   527 WIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQN 591
            |:..:|..|||||::|||.|..|||....||..|...:.|:.:....||||.:|....:|   :|
 Worm   187 WVSTHISSFGGDPKNVTLFGQSAGAVCADLLNLSPYSRDLFHKLIIMSGSAHVPFAIRTE---EN 248

  Fly   592 EQLMATLECADIQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGSRHEWLV-------LDG 649
            :.|:         |:..|.|.....:.....|.|..:||..:....:|.:|...:       |||
 Worm   249 QALV---------CMEYARSRGFSGSGSAELLEFFENLPIEKLLEKTGLKHTVSIDLSFAPNLDG 304

  Fly   650 DVVFEHPSDTWKREQANDKPVLVMGATAHEAHTEKLRELHANWTREEVRAYLENSQIGALGLTDE 714
            | .|..|.:..:|| ...|||:| |....|.......:.......|..:..:|:...|.:....|
 Worm   305 D-FFPKPLEELRRE-TRKKPVIV-GMMEDEGLITAFADGDFTTCEENFKRRVESEYRGDVVENPE 366

  Fly   715 VIEK--------------------------YNASSYASLVSIISDIRSVCPLLTNARQQPSVPFY 753
            .::|                          |||....|..|:             ||....|.||
 Worm   367 NVQKNIMNFYTNYCDESEERKLVDYIGHSVYNAGVLLSAESL-------------ARAGNCVYFY 418

  Fly   754 VV----TQGEGPDQLATVDADVQAILGRYEP-----HTVEQRRFVSAMQQLFYYYVSHGTVQSFV 809
            |.    ..|.||             :|...|     |..|.|           |.:..|....|.
 Worm   419 VFDFWNPDGFGP-------------VGSIVPFKGAAHCSELR-----------YIIGEGVYSKFD 459

  Fly   810 QNRR 813
            .|.:
 Worm   460 ANEK 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	131/524 (25%)
cest-31	NP_504692.3	COesterase	16..522	CDD:395084	131/524 (25%)