Protein Alignment Nrt and cest-8

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 501
• Identity: 116/501 - (23%)
• Similarity: 188/501 - (37%)
• Gaps: 133/501 - (26%)

  Fly   365 TGCGPVEGVKE--DGA---FAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ 424
            |..|.:.|:.|  |.|   |.|:.:|:||||:..||:.|.:.:|.    |:..|.....|..|
 Worm    23 TSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLRFAPPQKLDH----WDGILDASVYSAAC-- 81

  Fly   425 RLGNGT----TVGDEDCLYLDVVTPHVRYNNPLPVVVLI--GA---ESLAGPSPGILRPSARYSR 480
             :.|.|    :..:|||||:::.|......:...|:|..  ||   ||....|...:..  ||..
 Worm    82 -MSNSTLTTQSYVNEDCLYINIFTSEKCLKSKCSVIVYFHGGAYNTESATMFSDRFILD--RYVH 143

  Fly   481 SHDVIFVRPNFRLGVFG--FLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVT 543
             .|||||.|..||||||  :...:|...|       |..:.|.|..|:::...|.:|||||:.||
 Worm   144 -EDVIFVIPAVRLGVFGQLYFGPNAYLTE-------NLFMFDAILALDFVHNEISNFGGDPEKVT 200

  Fly   544 LLGHRAGATLVTLLVNSQKVK---GLYTRAWASSGSAILPGKPL-----------------SESG 588
            ::||.:|.|||..|..|..|.   .|:.:....|.:.:.....|                 ::..
 Worm   201 IMGHSSGGTLVEALGFSSMVDPELKLFQQMIMLSSTGMFGFDDLVIDNSFTIVEKLGCFNGTKEE 265

  Fly   589 KQNEQLMATLEC-------------ADIQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGS 640
            :....:..||:|             ..::.:.:.|.:.|....|
 Worm   266 RNTVNVAETLDCMRHIDGYEILRVQQKMELMDQLSFKYLLRGAP--------------------- 309

  Fly   641 RHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHEAH--TEKLRELHANWTREE-----VR 698
               :::|:|::     :|..|.....:   .:.|.|.||..  |||...:...:...|     .|
 Worm   310 ---FMLLNGNI-----ADLKKNTSPRN---AIFGTTEHEFFDVTEKYLYITVTFLDYENPVAVAR 363

  Fly   699 AY----LENSQIGALGLTDEVIEKYNASSYASLVSIISDIRSVCPLLTNARQQPSVPFYVVTQGE 759
            .|    ::|.:....| ....|....|:..|::.:..:|:     .|...||..||..
 Worm   364 NYDGRLMKNMETMITG-DSAAIFVSTATCAAAMANAGADV-----FLFETRQSYSVHV------- 415

  Fly   760 GPDQLATVDADVQAILGRYEPH--TVEQRRFVSAMQQLFYYYVSHG 803
                     :|:|..:|.:..|  |::.....|...:|...:..||
 Worm   416 ---------SDMQYFIGNHCAHNRTIDIDILDSFYSKLLTNFTKHG 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	116/501 (23%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	116/501 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900