Protein Alignment Nrt and cest-33

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 138/548 - (25%)
• Similarity: 204/548 - (37%)
• Gaps: 147/548 - (26%)

  Fly   341 IGYVLTHETLTSPPLREGRYIMAVTGCGPVEG--VKEDGAF--AFRGIPYAKPPVDRLRWKPAEL 401
            :|..|:|.|    |.:....:.|  .||||.|  .|.|...  .:.|||||||||..||:|....
 Worm     1 MGGFLSHLT----PEQNVEALKA--SCGPVRGNIYKHDDVIVDGYLGIPYAKPPVGELRFKKPVT 59

  Fly   402 IDDINMCWNDTLQTHNSSVVCTQRLGNGTTVG-------DEDCLYLDVVTPH---VRYNNPLPVV 456
            :|    .|.:....:.....|.|..|.....|       :..||.|:|.||.   ..:.|..||:
 Worm    60 VD----VWTEIKDCYKYGPACVQTGGFEQIAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGRPVM 120

  Fly   457 VLIG-------------AESLAGPSPGILRPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEA 508
            |.|.             |.||:|..|           ..||:.|..|:||||||||.    |.:.
 Worm   121 VYIHGGGYELCASSDFCAYSLSGTLP-----------LKDVVVVSINYRLGVFGFLT----TGDN 170

  Fly   509 HPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWAS 573
            ..|  ||:.|.|....|.|::.:|..|||||..||:.|..||.....||..|...:.|:.|....
 Worm   171 VCP--GNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSAGGASTDLLSLSPHSRDLFQRFIPI 233

  Fly   574 SGSAILPGKPLSESGKQNEQLMATLECADIQCL--REASSERLW--AATPDTWLHFPVDLPQPQE 634
            ||:|..   ..:....:| |.....|.|:....  |::|:...|  ..:|:|.
 Worm   234 SGTAHC---DFAIRASEN-QAKIFREFAEFHGFSGRDSSALFKWYQEQSPETL------------ 282

  Fly   635 ANASGSRHE---WLV----LDGDVVFEHPSDTWKREQANDKPVLVMGATAHEAHTEKLRELHANW 692
            :|..|.:..   :|.    |||| .|..|.|..::|.  .|..::.|.|.:|.  ..|..::..:
 Worm   283 SNVKGYKKSISGFLTFIPNLDGD-FFPKPLDELRKEA--PKKQMMTGVTEYEG--LMLASMNPAF 342

  Fly   693 TREEVRAYLENSQIGALGLT---------------DEVIEKYNASSYASLVSIISDI---RSVCP 739
            :..:|            |||               || |:|.....|...|....::   :.:|.
 Worm   343 SPADV------------GLTLMPQGIYGKDVVSNPDE-IQKIFYEKYVEGVDKSDELAMRKKLCE 394

  Fly   740 LL-------------TNARQQPSVPFYVVTQGEGPDQLATVD-----------ADVQAILG---- 776
            .|             .||.:..:..::...:...||.....|           .:::.:||
 Worm   395 ALGDEFFNVGVIQAAKNAAKHGNEVYFYTFEYVNPDSFGMWDGMMPFKAAVHCTELRYLLGEGVY 459

  Fly   777 -RYEPHTVEQRRFVSAMQQLFYYYVSHG 803
             ::|| |.|.|:.:.....||..:..:|
 Worm   460 SKFEP-TEEDRKVMETTTTLFSNFAKYG 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	133/527 (25%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	133/529 (25%)