DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nrt and cest-6

DIOPT Version :9

Sequence 1:	NP_001189121.1	Gene:	Nrt / 39873	FlyBaseID:	FBgn0004108	Length:	846	Species:	Drosophila melanogaster
Sequence 2:	NP_501070.1	Gene:	cest-6 / 177459	WormBaseID:	WBGene00020688	Length:	583	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	70/253 - (27%)
Similarity:	104/253 - (41%)	Gaps:	51/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   329 FGILLFVLLLGVIGY------VLTHETLTSPPLREGRYIMAVTGCGPVEGVKEDGAFAFRGIPYA 387
            |.:|:||||:....|      |:|                  |..|.:.|.:......|:.||:|
Worm     4 FDMLIFVLLIVYSAYKSCEAGVIT------------------TSLGSINGNQIGSYQTFKKIPFA 50

  Fly   388 KPPVDRLRW-KP--AELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVG------DEDCLYLDVV 443
            |||:.:||: ||  ||.       |...|........|   :.|.:|..      |||||::::.
Worm    51 KPPIGKLRFQKPMAAEK-------WEGILNATEYGPAC---MSNSSTSKSPQKWIDEDCLHINIF 105

  Fly   444 TPHVRYNNP-LPVVVLIGAESLAGPSPGILRPSARYS--RSHDVIFVRPNFRLGVFGFLALDALT 505
            |.....::. ..||..:....|...|..:......:.  .|.|||.|.|.||||:|....:
Worm   106 TTDTCLSSKNCSVVFYVHGGELVYDSAVMFEDKYLFDTFSSRDVILVIPAFRLGLFSHFVV---- 166

  Fly   506 KEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKV 563
             |.......|.||.||:..|.::|..|.:|||....||..||..|..:|:::..|.::
Worm   167 -EDQNVAPNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHSYGGHVVSVMAFSTEI 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	61/214 (29%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	63/232 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900