Protein Alignment Nrt and cest-25

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 138/549 - (25%)
• Similarity: 219/549 - (39%)
• Gaps: 149/549 - (27%)

  Fly   342 GYVLTHETLTSPPLREGRYIMAVTGCGPVEGVK-----EDGAFAFRGIPYAKPPVDRLRW---KP 398
            |.|..|.|...||.|:     .:|..||:||.:     |....||:|||||.||:..||:   :|
 Worm     3 GTVSKHTTPHYPPSRQ-----VLTSYGPIEGRRLIHEGEKQVDAFQGIPYAAPPIGNLRFALPQP 62

  Fly   399 AELIDDINMCWNDTLQTHNSSVVCTQR---LGNGTTVGDEDCLYLDVVTPHVRYNNP--LPVVVL 458
            .|.       |.:..:|.:......|:   |...|:...||.|.|::.||.....|.  .||::.
 Worm    63 HEK-------WTEVRETKSFGARGIQKDHVLSPKTSPQSEDNLTLNIFTPVWTPKNETGFPVILY 120

  Fly   459 IGAESLAGPSPGILRPSA---------RYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSG 514
            |       ...|.:..||         ::..:.||:.|...:|||..||..    |.::..|  .
 Worm   121 I-------HGGGFVSDSAHKYGDMSICQHLVTKDVVVVTIQYRLGFLGFWT----TGDSSIP--D 172

  Fly   515 NYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGS--- 576
            |.||.|::..|.|:|.||..|.|||.::||:|..||...|..|..|...:.|:.:.....|:
 Worm   173 NVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVSRDLFQKVIPMGGNASC 237

  Fly   577 --AILPGKPLSESGKQNEQL-----MATLECADIQCLREASSERLWAATPDTWLHF-PVDLPQPQ 633
              ||.| :||:....:.:::     |.||:.  ::.|||..:::..:|     |:. .||.....
 Worm   238 SWAIHP-RPLNACRNRAQEIGVFDGMNTLDW--VEKLRELPADKFASA-----LNMEAVDTKTDP 294

  Fly   634 EANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGA-------------TAHEAH---- 681
            |. ..|.:::.|.:...|:       ..|::|..||.|:..|             |.|..|
 Worm   295 EL-LIGPKYDNLFIPRPVM-------ELRKEAPMKPRLLGCAKSEGLVFAFFGLNTKHPLHAVQQ 351

  Fly   682 ------TEKLRELHANWTREEVRAYLENS-----QIGALGLTDEVIEKYNASSYASLVSIISDI- 734
                  :|||..|.|       |.|.|.:     :||    ||...|::.    .::|.:..|.
 Worm   352 DVSAILSEKLFPLKA-------RDYQEKALEKLIEIG----TDHSKEEWQ----RAMVDLKGDSF 401

  Fly   735 ------RSVCPLLTNARQQPSVPFYVVT------QGEG------PDQLATVDADVQAILGRYEPH 781
                  ::|..:|   ..|||.|.|:.:      :..|      |.:.||...|:..::|.   |
 Worm   402 LNVGIQQNVLDVL---ETQPSTPIYMYSFDYCNPKAYGIMGFKLPFKDATHCTDISYVVGN---H 460

  Fly   782 TV-------EQRRFVSAMQQLFYYYVSHG 803
            .|       |..:.:....:|:..:..:|
 Worm   461 IVNSFDFNEEDYKMIEITTRLWTNFAKYG 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	131/529 (25%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	131/534 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900