Protein Alignment Nrt and Ces2c

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_598270.2
• Gene: Ces2c / 171118
• RGDID: 621510
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 147/598 - (24%)
• Similarity: 232/598 - (38%)
• Gaps: 165/598 - (27%)

  Fly   327 IVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEG----VKED--GAFAFRGIP 385
            ::||:||.::      :|...::..|..:|       .|..|.|.|    |::.  |...|.|||
  Rat    13 VLFGLLLILI------HVWGQDSPESSSIR-------TTHTGQVRGKLDHVRDTKAGVHTFLGIP 64

  Fly   386 YAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVG-------------DEDC 437
            :||.||..||:.|.|..:.    |:......:...:|.|.:.....||             .|||
  Rat    65 FAKAPVGPLRFAPPEDPEP----WSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDC 125

  Fly   438 LYLDVVTP-HVRYNNPLPVVVLIGAESL----AGPSPGILRPSARYSRSHDVIFVRPNFRLGVFG 497
            |||::.|| |....:.|||:|.|...:|    |....|.|     .:.:.|::.|...:||||.|
  Rat   126 LYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSL-----LAVNEDLVVVAIQYRLGVLG 185

  Fly   498 FLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQK 562
            |.:    |.:.|  ..||:...|.:|.|.|::.||.||||:|..||:.|..||.|.|:..|.|..
  Rat   186 FFS----TGDEH--ARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPM 244

  Fly   563 VKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATL---ECAD----IQCLREASS------ERL 614
            .:||:..|...||.|:||.. :||:.:.....:|.|   |..|    ::|||..|.      .::
  Rat   245 SQGLFHGAIMESGVALLPDL-ISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKV 308

  Fly   615 WAATPDTWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGATAHE 679
            :...|                         .|:||:.:..||.:....|..:..|.:: |....|
  Rat   309 FKMIP-------------------------AVVDGEFLPRHPKELLASEDFHPVPSII-GVNTDE 347

  Fly   680 ---------AHTEKLRELHANWTREEVRAYLENS--------QIGALGLTDEVIEKYNASS---- 723
                     ...:.::||    :||.::|.|:::        :.|     |.::|:|..::
  Rat   348 YCCTIPMVMGTAQIIKEL----SRENLQAVLKDTAAQMMLPPECG-----DLLMEEYMGNTDDPQ 403

  Fly   724 -----YASLVSIISDIRSVCPLLTNAR-QQPSVPFYVVTQGEGPDQLATV--------DAD-VQA 773
                 ||.:   :.|...|.|.|..|. |:...|.|.......|.....|        .|| |..
  Rat   404 TLQIQYAEM---MGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPF 465

  Fly   774 ILGRY-----EPHTVEQRRFVSAMQQLFYYYVSHGTVQSFVQNRRVINVGQDAQPEEDYLPCNYW 833
            :.|.:     ...|.|::.....|.:.:..:..||                  .|..:.||  ||
  Rat   466 VFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHG------------------NPNSEGLP--YW 510

  Fly   834 ISKDIVPRYARVD 846
            ...|...:|.::|
  Rat   511 PVLDHDEQYLQLD 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412
		alpha/beta hydrolases	362..832	CDD:473884	135/547 (25%)
Ces2c	NP_598270.2	COesterase	32..540	CDD:395084	142/573 (25%)