Protein Alignment Nrt and LOC1281827

DIOPT Version :10

• Sequence 1: NP_476798.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_061505289.1
• Gene: LOC1281827 / 1281827
• VectorBaseID: AGAMI1_012788
• Length: 737
• Species: Anopheles gambiae
• Alignment Length: 752
• Identity: 168/752 - (22%)
• Similarity: 250/752 - (33%)
• Gaps: 243/752 - (32%)

  Fly   112 KKIPIGGLKLPGFFMKNKPKADGDGAEGELLEKEKEEDKDKEANG--------DAATGSGKDEQK 168
            :.:|:|.|.:....:...|.|...|...||            .||        .||.|.|...|.
Mosquito    16 RMVPLGLLGVTALLLILPPSALVQGRHHEL------------NNGAAIGSHQLSAAAGVGLASQS 68

  Fly   169 SRPG-LGERLRSFFARKPSAEKEKKQLVNGDADAKSEATAEATPAEDASDA--PPKRGLLNAIKL 230
            ::.| |...:.|......::......|::..|:   :..|..|.::|| ||  .|..|...::::
Mosquito    69 AQSGSLASGVMSSVPAAGASSSSSSSLLSSSAE---DDVARITLSKDA-DAFFTPYIGHGESVRI 129

  Fly   231 PIANMIPKKKSNDDVELGLGKAGLASMETLDDSLKDQDTVDRAPVKTNGTEELKGELKDEKLAAE 295
                        .|.|||          ||:.            |.:..|...:|..:.|
Mosquito   130 ------------IDAELG----------TLEH------------VHSGATPRRRGLTRRE----- 155

  Fly   296 EKLAAEEEEQNRPVSLLT---RLRGYKCSVDDALIVFGILLFVLLLGVIGYVLTHETLTSPPLRE 357
               :..:...|.|:.:.|   |:||.                              |:.:|
Mosquito   156 ---SNSDANDNDPLVVNTDKGRIRGI------------------------------TVDAP---- 183

  Fly   358 GRYIMAVTGCGPVEGVKEDGAFAFRGIPYAKPPVDRLRW---KPAELIDDINMCWNDTLQTHNSS 419
                         .|.|.|   .:.|||||:|||..||:   :|||.       |...|.|....
Mosquito   184 -------------SGKKVD---VWLGIPYAQPPVGPLRFRHPRPAEK-------WTGVLNTTTPP 225

  Fly   420 VVCTQ------------RLGNGTTVGDEDCLYLDVVTPHVRYNNPLPVVVLIGAESLAGPSPGIL 472
            ..|.|            .:.|..|...|||||::||.|..|..|...::.:.|....:|.:...:
Mosquito   226 NSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIFGGGFYSGTATLDV 290

  Fly   473 RPSARYSRSHDVIFVRPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGG 537
            ......:...:||.|...:|:...|||.|..      |...||..|.|....|.|::.||..|||
Mosquito   291 YDHRALASEENVIVVSLQYRVASLGFLFLGT------PEAPGNAGLFDQNLALRWVRDNIHRFGG 349

  Fly   538 DPQSVTLLGHRAGATLVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLECAD 602
            ||..|||.|..|||..|:|.:.|...:.|:.||...|||...|...:|.            |.|.
Mosquito   350 DPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWALVSR------------EEAT 402

  Fly   603 IQCLREASSERLWAATPDTWLHFPVDLPQPQEANASGSRH-----EW-----------LVLDGDV 651
            ::.||.|.:    ...|    |.|..|....|.......|     ||           .|:||..
Mosquito   403 LRALRLAEA----VGCP----HEPSKLSDAVECLRGKDPHVLVNNEWGTLGICEFPFVPVVDGAF 459

  Fly   652 VFEHPSDTWKREQAN---DKPVLVMGATAHEAH-------TEKLR-ELHANWTREEVRAYLENSQ 705
            :.|.|    :|..|:   .|..::.|:...|.:       ||.|| |.....||||
Mosquito   460 LDETP----QRSLASGRFKKTEILTGSNTEEGYYFIIYYLTELLRKEEGVTVTREE--------- 511

  Fly   706 IGALGLTDEVIEKYNASSYASLVSIISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDAD 770
                                    .:..:|.:.|.:..|.:|..|  :..|....||...:....
Mosquito   512 ------------------------FLQAVRELNPYVNGAARQAIV--FEYTDWTEPDNPNSNRDA 550

  Fly   771 VQAILGRYEPH---TVEQ--RRFVSAMQQLFYYYVSH 802
            :..::|.|  |   .|.:  :|:......::.|..:|
Mosquito   551 LDKMVGDY--HFTCNVNEFAQRYAEEGNNVYMYLYTH 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_476798.1	PTZ00121	<3..>222	CDD:173412	27/120 (23%)
		alpha/beta hydrolases	362..832	CDD:473884	122/488 (25%)
LOC1281827	XP_061505289.1	None