Protein Alignment Nrt and Ces1d

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 144/591 - (24%)
• Similarity: 241/591 - (40%)
• Gaps: 146/591 - (24%)

  Fly   331 ILLFVLLLGVIGYVLTHETLTSPPLRE-------GRYIMAVTGCGPVEGVKEDGAFAFRGIPYAK 388
            :.||:......||.      :|||:..       |:|:       .:||..:..| .|.|||:||
  Rat     7 VWLFLAACTAWGYP------SSPPVVNTVKGKVLGKYV-------NLEGFAQPVA-VFLGIPFAK 57

  Fly   389 PPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQRLGNGTTVGD--------------EDCLY 439
            ||:..||:.|.:..:.    ||....|.:...:|:|....|..:.:              |||||
  Rat    58 PPLGSLRFAPPQPAEP----WNFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLY 118

  Fly   440 LDVVTP-HVRYNNPLPVVVLIGAESLAGPSPGILRPSARY-----SRSHDVIFVRPNFRLGVFGF 498
            |:|.|| .:..|:.|||:|.|....|      ::..::.|     |...:|:.|...:|||::||
  Rat   119 LNVYTPADLTKNSRLPVMVWIHGGGL------VVGGASTYDGQVLSAHENVVVVTIQYRLGIWGF 177

  Fly   499 LALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGATLVTLLVNSQKV 563
            .:    |.:.|  :.||:...|.:|.|:|::.||.:|||:|.|||:.|..||...|:.||.|...
  Rat   178 FS----TGDEH--SQGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSALVLSPLA 236

  Fly   564 KGLYTRAWASSGSAILPGKPLSESGKQNEQLMATLE-CAD------IQCLREASSERLWAATPDT 621
            |.|:.||.:.|| .:|....::...|....|:|||. |..      :.|||:.:.:.|...:...
  Rat   237 KNLFHRAISESG-VVLTSALITTDSKPIANLIATLSGCKTTTSAVMVHCLRQKTEDELLETSLKL 300

  Fly   622 WLHFPVD-LPQPQEANASGSRHEWL--VLDGDVVFEHPSDTWKREQANDKPVLV----------- 672
            .| |.:| |..|:|:      :.:|  |:||.|:.:.|.:....:..|..|.:|
  Rat   301 NL-FKLDLLGNPKES------YPFLPTVIDGVVLPKTPEEILTEKSFNTVPYIVGINKQEFGWII 358

  Fly   673 ---MGATAHEAHTEKLRELHANWTREEVRAYLENSQIGALGLTDEVI----EKY--NASSYASLV 728
               ||....|...::.......|     ::|      ..|.:::::|    |||  .....|...
  Rat   359 PTLMGYPLSEGKLDQKTAKSLLW-----KSY------PTLKISEKMIPVVAEKYFGGTDDPAKRK 412

  Fly   729 SIISDIRSVCPLLTNARQQPSVPFYVVTQGEGPDQLATVDADVQAILGRYEPHTVEQRRFVSAMQ 793
            .:..|:  |..::.      .||..:|::...       ||.....:..:|    .:..|||||:
  Rat   413 DLFQDL--VADVMF------GVPSVMVSRSHR-------DAGAPTFMYEFE----YRPSFVSAMR 458

  Fly   794 ----------QLFYY----YVSHGTVQSFVQNRRVI-----NVGQDAQPEEDYLPCNYWISKDIV 839
                      :||..    ::..|..:......:::     |..::..|....||  :|...|..
  Rat   459 PKTVIGDHGDELFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGSPNGGGLP--HWPEYDQK 521

  Fly   840 PRYARV 845
            ..|.::
  Rat   522 EGYLKI 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	132/538 (25%)
Ces1d	NP_579829.3	COesterase	24..545	CDD:278561	138/568 (24%)
		Aes	<121..>239	CDD:223730	44/129 (34%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010