Protein Alignment Nrt and Ces2a

DIOPT Version :9

• Sequence 1: NP_001189121.1
• Gene: Nrt / 39873
• FlyBaseID: FBgn0004108
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 575
• Identity: 148/575 - (25%)
• Similarity: 227/575 - (39%)
• Gaps: 140/575 - (24%)

  Fly   312 LTRLRGYKCSVDDALIVFGILLFVLLLGVIGYVLTHETLTSPPLREGRYIMAVTGCGPVEG---- 372
            |.||.|:.|     ::..|:||  ||..|      |...::.|:|.       |..|.|.|
Mouse     3 LARLPGWLC-----VVACGLLL--LLQHV------HGQDSASPIRN-------THRGQVRGSFVH 47

  Fly   373 VKE--DGAFAFRGIPYAKPPVDRLRWKPAELIDDINMCWNDTLQTHNSSVVCTQ----RLGNGTT 431
            ||:  .|..||.|||:|||||..||:.|.|..:.    |:......:...:|.|    .|.:...
Mouse    48 VKDTKSGVHAFLGIPFAKPPVGLLRFAPPEDPEP----WSGVRDGTSQPAMCLQPDIMNLEDAKE 108

  Fly   432 VG--------DEDCLYLDVVTP-HVRYNNPLPVVVLIGAESLAGPSPGILRPSARYSRSHDVIFV 487
            :.        .||||||::.|| |.:..:.|||:|.|....|...|.. :...::.:.:.:::.|
Mouse   109 MNLILPPISMSEDCLYLNIYTPTHAQEGSNLPVMVWIHGGGLVVGSAS-MNDVSKLAATEEIVIV 172

  Fly   488 RPNFRLGVFGFLALDALTKEAHPPTSGNYALTDIIAVLNWIKLNIVHFGGDPQSVTLLGHRAGAT 552
            ...:||||.||.:    |.:.|  ..||:...|.:|.|.|::.||.:|||:...||:.|..||.|
Mouse   173 AIQYRLGVLGFFS----TGDQH--ARGNWGYLDQVAALRWVQKNIAYFGGNRDRVTIFGVSAGGT 231

  Fly   553 LVTLLVNSQKVKGLYTRAWASSGSAILPGKPLSESGKQNEQLMATL---ECAD----IQCLREAS 610
            .|:..:.|...|||:..|...||.|:||.. :|::.:...:.:|.|   |..|    |.|||..|
Mouse   232 SVSSHILSPMSKGLFHGAIMQSGVALLPDL-ISDTSEVVYKTVANLSGCEATDSEALIHCLRAKS 295

  Fly   611 SERLWAATPDTWLHFPVDLPQPQEANASGSRHEWLVLDGDVVFEHPSDTWKREQANDKPVLVMGA 675
            .:.:.|.. ..:...|.                  |:||:.:.:||.:.......:..|.:: |.
Mouse   296 KQEILAIN-QVFKMIPA------------------VVDGEFLPKHPQELLTSMDFHPVPSII-GV 340

  Fly   676 TAHEA-----------HTEKLRELHANWTREEVRAYLENSQIGALGLTDE----VIEKYNASS-- 723
            ...|.           |..|      |.|||.:.|.|:|: ...:.|..|    ::|:|...:
Mouse   341 NTDECGWGVPMFMGLDHIIK------NITRETLPAVLKNT-AARMMLPPECSHLLVEEYMGDTED 398

  Fly   724 ----YASLVSIISDIRSVCPLLTNA---RQQPSVPFYVVTQGEGPDQLATVDADVQAILGRYEPH 781
                .|....::.|...|.|.|..|   |.|..|.||....             :.:.:....|.
Mouse   399 PETLQAQFREMLGDFMFVIPALQVAHFQRSQAPVYFYEFQH-------------LSSFIKHVRPS 450

  Fly   782 TVEQRRFVSAMQQLFYYYVSHGTVQSFVQNRRVINVGQDAQPEEDYLP---CNYW 833
            .|:               ..||...:||....:.::..|...||:.|.   ..||
Mouse   451 HVK---------------ADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYW 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nrt	NP_001189121.1	Abhydrolase	362..832	CDD:304388	132/522 (25%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:278561	136/535 (25%)
		Aes	<127..>230	CDD:223730	34/109 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910