DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9701 and kl

DIOPT Version :9

Sequence 1:	NP_648918.1	Gene:	CG9701 / 39872	FlyBaseID:	FBgn0036659	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_021335093.1	Gene:	kl / 562316	ZFINID:	ZDB-GENE-110221-1	Length:	990	Species:	Danio rerio

Alignment Length:	530	Identity:	183/530 - (34%)
Similarity:	268/530 - (50%)	Gaps:	78/530 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVK 90
            ||:.|:|.||:::|.:||.|..|.||:||||  |.|.....|.|  |||.:||||....|::.::
Zfish    49 FPDKFMWAVGTAAYSVEGAWEKDGKGKSIWD--TFTRGGTRVSR--GDVGSDSYHNIPGDLRALQ 109

  Fly    91 ELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQEL-G 154
            :|.|..||||||||||...|.....:..|::||.|||..|....:.|:||:|||:||..||.| |
Zfish   110 QLGVSHYRFSLSWPRIFSNGTKESYNDKGVEYYKNLIRGLKDIKVQPVVTLYHWDLPDSLQTLFG 174

  Fly   155 GWTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHN 219
            ||:|..::.||:|||....:.:|..||.|.|::.|:.|..||||...:||.........:..|||
Zfish   175 GWSNSVMVELFRDYADFCFKTFGSDVKFWITIDNPFVVAWHGYGTGVVAPGIKNDSDLPFRVGHN 239

  Fly   220 LLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSK 284
            ||||||...|:|.|.::..||||:.:.|.:.|.:| .....|.|:|.:|::.|.:|||..|:| .
Zfish   240 LLKAHAAAWHLYDERYRAAQGGRVSMALGSHWIKP-SRTRQESRKACQRSLNFVLGWFARPLF-V 302

  Fly   285 HGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGK 349
            .|:||..|.:.:.:           |||.||..|...:.||:|||.:         |:|
Zfish   303 DGDYPPCMKDNLTH-----------RLPSFTEAESAYVNGTADFFAL---------SHG------ 341

  Fly   350 FPVPSF---NHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSDR 411
             |..||   |..:...::::                .|:..||.|:..|||.|.|.|.|:|....
Zfish   342 -PALSFQLINDSLRFGQTED----------------LGLRMLLYWVRAEYNNPPIFVVESGWYGS 389

  Fly   412 GG--LEDYARVDYYNLYLSAVLDAME-DGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQ 473
            |.  .:|...:.|...::...|.|:. |..|:.||.||||:|.|||...::.:.||::||||:|.
Zfish   390 GNTKTKDAKHMYYLKRFIMETLKAIHVDRVNVIGYTAWSLLDGYEWYREYAIRRGLFYVDFNTPD 454

  Fly   474 RTRTPKISARVFAQLCKTNTIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVS---------- 528
            ..|.||.||..:::|.:.|..     |:|.|.:.  |....|.:.....|:.::.
Zfish   455 LKREPKASATFYSKLIEKNGF-----PQLPENRP--AQGAFPCDFAWGVAANSIQVDTTPTQFTD 512

  Fly   529 -----WSLMG 533
                 |::.|
Zfish   513 TNVYVWNISG 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9701	NP_648918.1	Glyco_hydro_1	22..492	CDD:304882	174/472 (37%)
kl	XP_021335093.1	Glyco_hydro_1	45..475	CDD:329037	175/474 (37%)
kl	XP_021335093.1	Glyco_hydro_1	485..930	CDD:329037	4/38 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257823at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100193
Panther	1	1.100	-	-	O	PTHR10353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3725
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.880